Verruculogen TR 1

Details

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Internal ID 3ad29bab-f708-4272-8903-b74b98fba0ac
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyridoindoles > Beta carbolines
IUPAC Name 23,24-dihydroxy-5-methoxy-12,12-dimethyl-9-(2-methylprop-1-enyl)-10,11-dioxa-8,15,21-triazahexacyclo[12.10.1.02,7.08,25.015,23.017,21]pentacosa-1(25),2(7),3,5-tetraene-16,22-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3
InChI Key LRXYHMMJJCTUMY-UHFFFAOYSA-N
Popularity 14 references in papers

Physical and Chemical Properties

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Molecular Formula C27H33N3O7
Molecular Weight 511.60 g/mol
Exact Mass 511.23185040 g/mol
Topological Polar Surface Area (TPSA) 114.00 Ų
XlogP 1.80

Synonyms

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Verruculogen TR 1
12771-72-1
TR1
DTXSID40925965
LRXYHMMJJCTUMY-UHFFFAOYSA-N
HB4120
F85598
Q11954479
10,10a-Dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-1,10,10a,14,14a,15b-hexahydro-12H-3,4-dioxa-5a,11a,15a-triazacycloocta[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione #
10,10a-Dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methylprop-1-en-1-yl)-1,10,10a,14,14a,15b-hexahydro-5H,12H-3,4-dioxa-5a,11a,15a-triazacycloocta[1,2,3-lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Verruculogen TR 1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.05% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.15% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.81% 95.56%
CHEMBL2581 P07339 Cathepsin D 96.41% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.02% 96.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 95.39% 93.40%
CHEMBL1902 P62942 FK506-binding protein 1A 95.07% 97.05%
CHEMBL5608 Q16288 NT-3 growth factor receptor 94.90% 95.89%
CHEMBL1871 P10275 Androgen Receptor 93.86% 96.43%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.96% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.45% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.26% 85.14%
CHEMBL4208 P20618 Proteasome component C5 86.88% 90.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 86.31% 91.03%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.91% 94.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 84.84% 97.25%
CHEMBL241 Q14432 Phosphodiesterase 3A 83.81% 92.94%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.20% 97.14%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.92% 92.62%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.44% 97.09%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 81.31% 93.00%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.92% 82.38%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 104862
LOTUS LTS0225904
wikiData Q11954479