Veraguamide C

Details

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Internal ID c5aeeebf-e10d-4abb-964c-bdce4ffdcb7b
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3S,6S,9S,12S,13R,16S,19S)-3-[(2S)-butan-2-yl]-7,12,17-trimethyl-13-pent-4-ynyl-6,9,16-tri(propan-2-yl)-4,14-dioxa-1,7,10,17-tetrazabicyclo[17.3.0]docosane-2,5,8,11,15,18-hexone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C37H60N4O8/c1-13-15-16-19-27-25(10)32(42)38-28(21(3)4)34(44)40(12)30(23(7)8)37(47)49-31(24(9)14-2)35(45)41-20-17-18-26(41)33(43)39(11)29(22(5)6)36(46)48-27/h1,21-31H,14-20H2,2-12H3,(H,38,42)/t24-,25-,26-,27+,28-,29-,30-,31-/m0/s1
InChI Key DOTFUBBQWCBCSH-AVCHBABLSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C37H60N4O8
Molecular Weight 688.90 g/mol
Exact Mass 688.44111488 g/mol
Topological Polar Surface Area (TPSA) 143.00 Ų
XlogP 5.90

Synonyms

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CHEBI:67332
CHEMBL1783107
DTXSID101047212
Q27135789

2D Structure

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2D Structure of Veraguamide C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.79% 98.95%
CHEMBL3837 P07711 Cathepsin L 98.64% 96.61%
CHEMBL333 P08253 Matrix metalloproteinase-2 98.62% 96.31%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.55% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.34% 96.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 96.69% 90.08%
CHEMBL4588 P22894 Matrix metalloproteinase 8 95.89% 94.66%
CHEMBL5203 P33316 dUTP pyrophosphatase 93.92% 99.18%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 93.83% 82.38%
CHEMBL1902 P62942 FK506-binding protein 1A 92.44% 97.05%
CHEMBL1978 P11511 Cytochrome P450 19A1 92.20% 91.76%
CHEMBL1937 Q92769 Histone deacetylase 2 92.01% 94.75%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 91.71% 90.71%
CHEMBL321 P14780 Matrix metalloproteinase 9 91.70% 92.12%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.39% 95.56%
CHEMBL4072 P07858 Cathepsin B 91.05% 93.67%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.67% 97.09%
CHEMBL228 P31645 Serotonin transporter 90.45% 95.51%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.04% 85.14%
CHEMBL255 P29275 Adenosine A2b receptor 87.88% 98.59%
CHEMBL2189110 Q15910 Histone-lysine N-methyltransferase EZH2 87.38% 97.50%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.58% 95.89%
CHEMBL1949 P62937 Cyclophilin A 85.67% 98.57%
CHEMBL332 P03956 Matrix metalloproteinase-1 85.56% 94.50%
CHEMBL217 P14416 Dopamine D2 receptor 85.45% 95.62%
CHEMBL2996 Q05655 Protein kinase C delta 84.99% 97.79%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 84.96% 95.36%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 84.47% 93.03%
CHEMBL325 Q13547 Histone deacetylase 1 83.88% 95.92%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 83.35% 96.38%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 83.18% 98.33%
CHEMBL2443 P49862 Kallikrein 7 83.08% 94.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.94% 100.00%
CHEMBL3310 Q96DB2 Histone deacetylase 11 81.32% 88.56%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 81.22% 95.50%
CHEMBL6136 O60341 Lysine-specific histone demethylase 1 81.16% 95.58%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 81.02% 100.00%
CHEMBL3691 Q13822 Autotaxin 80.90% 96.39%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.13% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 53355338
LOTUS LTS0224322
wikiData Q27135789