variecolorin A

Details

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Internal ID 6bc0c326-7407-4c7c-87d0-9318a92625e8
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives
IUPAC Name (3Z,6S)-3-[[5-[(2R)-3-chloro-2-hydroxy-3-methylbutyl]-2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methylidene]-6-methylpiperazine-2,5-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C24H30ClN3O3/c1-7-23(3,4)20-16(12-18-22(31)26-13(2)21(30)28-18)15-10-14(8-9-17(15)27-20)11-19(29)24(5,6)25/h7-10,12-13,19,27,29H,1,11H2,2-6H3,(H,26,31)(H,28,30)/b18-12-/t13-,19+/m0/s1
InChI Key DKFVASQTSIAAEU-RKFKHAPCSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C24H30ClN3O3
Molecular Weight 444.00 g/mol
Exact Mass 443.1975695 g/mol
Topological Polar Surface Area (TPSA) 94.20 Ų
XlogP 4.20

Synonyms

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CHEMBL400169
DTXSID701101424
(3Z,6S)-3-[[5-[(2R)-3-Chloro-2-hydroxy-3-methylbutyl]-2-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]methylene]-6-methyl-2,5-piperazinedione
957780-65-3

2D Structure

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2D Structure of variecolorin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.88% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.38% 91.11%
CHEMBL2581 P07339 Cathepsin D 97.84% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.24% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.55% 95.56%
CHEMBL1951 P21397 Monoamine oxidase A 93.60% 91.49%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 93.53% 92.88%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.80% 96.09%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 90.36% 89.34%
CHEMBL1293255 P15428 15-hydroxyprostaglandin dehydrogenase [NAD+] 86.74% 83.57%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 86.54% 96.90%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 86.53% 91.71%
CHEMBL5103 Q969S8 Histone deacetylase 10 86.51% 90.08%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.63% 89.00%
CHEMBL3492 P49721 Proteasome Macropain subunit 83.57% 90.24%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.30% 93.03%
CHEMBL1937 Q92769 Histone deacetylase 2 81.02% 94.75%
CHEMBL4530 P00488 Coagulation factor XIII 80.84% 96.00%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 80.69% 92.29%
CHEMBL2179 P04062 Beta-glucocerebrosidase 80.31% 85.31%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 23655345
LOTUS LTS0072448
wikiData Q77506284