Varamine A
| Internal ID | 7dc017f6-b78b-4f6c-a910-aa40908a383c |
| Taxonomy | Organoheterocyclic compounds > Quinolines and derivatives > Benzoquinolines > Pyridoacridines > Pyrido[2,3,4-kl]acridines |
| IUPAC Name | N-[2-(12-methoxy-11-methylsulfanyl-8,14-diazatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2,4,6,9,11,13,15-octaen-10-yl)ethyl]propanamide |
| SMILES (Canonical) | |
| SMILES (Isomeric) | |
| InChI | InChI=1S/C22H23N3O2S/c1-4-17(26)23-11-10-15-19-18-14(13-7-5-6-8-16(13)25-19)9-12-24-20(18)21(27-2)22(15)28-3/h5-9,12,25H,4,10-11H2,1-3H3,(H,23,26) |
| InChI Key | ATGZYGBQIFBZRA-UHFFFAOYSA-N |
| Popularity | 3 references in papers |
| Molecular Formula | C22H23N3O2S |
| Molecular Weight | 393.50 g/mol |
| Exact Mass | 393.15109816 g/mol |
| Topological Polar Surface Area (TPSA) | 88.60 Ų |
| XlogP | 4.00 |
| 122093-14-5 |
| DTXSID10153495 |
| Propanamide, N-(2-(4-methoxy-5-(methylthio)-7H-pyrido(2,3,4-kl)acridin-6-yl)ethyl)- |
| Target | Value | Probability (raw) | Probability (%) |
|---|---|---|---|
| No predicted properties yet! | |||
Proven Targets:
| CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
|---|---|---|---|---|---|
| No proven targets yet! | |||||
Predicted Targets (via Super-PRED):
| CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
|---|---|---|---|---|
| CHEMBL240 | Q12809 | HERG | 98.56% | 89.76% |
| CHEMBL255 | P29275 | Adenosine A2b receptor | 98.38% | 98.59% |
| CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 98.35% | 91.11% |
| CHEMBL3251 | P19838 | Nuclear factor NF-kappa-B p105 subunit | 97.21% | 96.09% |
| CHEMBL4040 | P28482 | MAP kinase ERK2 | 95.74% | 83.82% |
| CHEMBL1806 | P11388 | DNA topoisomerase II alpha | 95.19% | 89.00% |
| CHEMBL2535 | P11166 | Glucose transporter | 95.18% | 98.75% |
| CHEMBL2581 | P07339 | Cathepsin D | 95.00% | 98.95% |
| CHEMBL4203 | Q9HAZ1 | Dual specificity protein kinase CLK4 | 94.34% | 94.45% |
| CHEMBL3038477 | P67870 | Casein kinase II alpha/beta | 93.64% | 99.23% |
| CHEMBL3060 | Q9Y345 | Glycine transporter 2 | 90.18% | 99.17% |
| CHEMBL4261 | Q16665 | Hypoxia-inducible factor 1 alpha | 89.89% | 85.14% |
| CHEMBL2635 | P51452 | Dual specificity protein phosphatase 3 | 89.41% | 94.00% |
| CHEMBL1914 | P06276 | Butyrylcholinesterase | 88.88% | 95.00% |
| CHEMBL1781 | P11387 | DNA topoisomerase I | 88.10% | 97.00% |
| CHEMBL1075094 | Q16236 | Nuclear factor erythroid 2-related factor 2 | 85.28% | 96.00% |
| CHEMBL3108638 | O15164 | Transcription intermediary factor 1-alpha | 84.73% | 95.56% |
| CHEMBL1937 | Q92769 | Histone deacetylase 2 | 83.54% | 94.75% |
| CHEMBL230 | P35354 | Cyclooxygenase-2 | 83.24% | 89.63% |
| CHEMBL1868 | P17948 | Vascular endothelial growth factor receptor 1 | 82.32% | 96.47% |
| CHEMBL4208 | P20618 | Proteasome component C5 | 82.10% | 90.00% |
| CHEMBL1287628 | Q9Y5S8 | NADPH oxidase 1 | 81.94% | 95.48% |
| CHEMBL3401 | O75469 | Pregnane X receptor | 81.57% | 94.73% |
| CHEMBL2094127 | P06493 | Cyclin-dependent kinase 1/cyclin B | 81.31% | 96.00% |
| CHEMBL2378 | P30307 | Dual specificity phosphatase Cdc25C | 80.02% | 96.67% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
To see more specific details click the taxa you are interested in.
| There are no matching plants. |
| PubChem | 180091 |
| LOTUS | LTS0082024 |
| wikiData | Q83020383 |