Upjohn culture 135bt

Details

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Internal ID 96ddc05c-aea8-45c2-9484-783790cd6d5c
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Phenylketones > Alkyl-phenylketones
IUPAC Name [5-(3-acetylanilino)-4-amino-3-(dimethylcarbamoylamino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl]methyl 2-hydroxy-6-methylbenzoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H38N4O8/c1-15-9-7-12-20(35)21(15)24(36)40-14-27(39)23(30-19-11-8-10-18(13-19)16(2)33)22(29)28(17(3)34,26(27,4)38)31-25(37)32(5)6/h7-13,17,22-23,30,34-35,38-39H,14,29H2,1-6H3,(H,31,37)
InChI Key WVIUOSJLUCTGFK-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C28H38N4O8
Molecular Weight 558.60 g/mol
Exact Mass 558.26896418 g/mol
Topological Polar Surface Area (TPSA) 195.00 Ų
XlogP 0.90

Synonyms

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23668-11-3
[5-(3-acetylanilino)-4-amino-3-(dimethylcarbamoylamino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl]methyl 2-hydroxy-6-methylbenzoate
NSC52947
SK 27773
U 15800
U-15800
CHEMBL1994414
1405-46-5
Benzoic acid, 2-hydroxy-6-methyl-, (3-((3-acetylphenyl)amino)-4-amino-5-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-5-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester
UNII-18P04J5471; Upjohn culture 135bt; 18P04J5471
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Upjohn culture 135bt

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.83% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.49% 96.09%
CHEMBL2535 P11166 Glucose transporter 92.88% 98.75%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.73% 86.33%
CHEMBL340 P08684 Cytochrome P450 3A4 92.62% 91.19%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 91.46% 93.03%
CHEMBL3401 O75469 Pregnane X receptor 91.18% 94.73%
CHEMBL2581 P07339 Cathepsin D 90.37% 98.95%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 90.32% 96.47%
CHEMBL221 P23219 Cyclooxygenase-1 90.23% 90.17%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.90% 99.23%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 89.76% 96.95%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 89.68% 98.75%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.07% 99.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.98% 95.56%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 86.93% 97.21%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 85.66% 91.24%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.23% 97.09%
CHEMBL1937 Q92769 Histone deacetylase 2 84.74% 94.75%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 84.69% 91.07%
CHEMBL5028 O14672 ADAM10 84.68% 97.50%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 84.44% 91.79%
CHEMBL1913 P09619 Platelet-derived growth factor receptor beta 83.91% 95.70%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 83.66% 96.00%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 83.51% 99.15%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.36% 89.00%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 82.56% 89.67%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.47% 95.89%
CHEMBL2996 Q05655 Protein kinase C delta 81.84% 97.79%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.06% 95.89%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 80.65% 93.10%
CHEMBL4208 P20618 Proteasome component C5 80.62% 90.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.33% 95.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 413861
LOTUS LTS0069912
wikiData Q105313548