Ulleungmycin A

Details

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Internal ID ed163874-74cb-42e7-b2e3-f7b57f517136
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name (2R)-2-[(2R,5S,8R,11R,14S,17S)-17-(3-aminopropyl)-14-[(2R)-butan-2-yl]-5-[(5-chloro-1H-indol-3-yl)methyl]-11-(3-methylbutyl)-3,6,9,12,15,18-hexaoxo-8-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadec-2-yl]-2-hydroxyacetamide
SMILES (Canonical) CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCC(C)C)C(C)C)CC2=CNC3=C2C=C(C=C3)Cl)C(C(=O)N)O)CCCN
SMILES (Isomeric) CC[C@@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N1)CCC(C)C)C(C)C)CC2=CNC3=C2C=C(C=C3)Cl)[C@H](C(=O)N)O)CCCN
InChI InChI=1S/C38H58ClN9O8/c1-7-20(6)29-37(55)43-25(9-8-14-40)33(51)48-30(31(49)32(41)50)38(56)45-27(15-21-17-42-24-13-11-22(39)16-23(21)24)35(53)46-28(19(4)5)36(54)44-26(34(52)47-29)12-10-18(2)3/h11,13,16-20,25-31,42,49H,7-10,12,14-15,40H2,1-6H3,(H2,41,50)(H,43,55)(H,44,54)(H,45,56)(H,46,53)(H,47,52)(H,48,51)/t20-,25+,26-,27+,28-,29+,30-,31-/m1/s1
InChI Key BEHXRGQIVXRKLZ-HKNNKDHJSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C38H58ClN9O8
Molecular Weight 804.40 g/mol
Exact Mass 803.4096875 g/mol
Topological Polar Surface Area (TPSA) 280.00 Ų
XlogP 2.70

Synonyms

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(2R)-2-((2R,5S,8R,11R,14S,17S)-17-(3-aminopropyl)-14-((2R)-butan-2-yl)-5-((5-chloro-1H-indol-3-yl)methyl)-11-(3-methylbutyl)-3,6,9,12,15,18-hexaoxo-8-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadec-2-yl)-2-hydroxyacetamide
(2R)-2-[(2R,5S,8R,11R,14S,17S)-17-(3-aminopropyl)-14-[(2R)-butan-2-yl]-5-[(5-chloro-1H-indol-3-yl)methyl]-11-(3-methylbutyl)-3,6,9,12,15,18-hexaoxo-8-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadec-2-yl]-2-hydroxyacetamide
RefChem:193000
CHEMBL4176662
CHEBI:208653

2D Structure

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2D Structure of Ulleungmycin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.31% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.94% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.06% 96.09%
CHEMBL2581 P07339 Cathepsin D 96.42% 98.95%
CHEMBL1937 Q92769 Histone deacetylase 2 95.88% 94.75%
CHEMBL4040 P28482 MAP kinase ERK2 95.85% 83.82%
CHEMBL213 P08588 Beta-1 adrenergic receptor 94.29% 95.56%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 93.57% 99.09%
CHEMBL4581 P52732 Kinesin-like protein 1 93.38% 93.18%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 92.18% 92.62%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 92.00% 92.88%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.83% 97.09%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 91.67% 90.71%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 91.41% 89.62%
CHEMBL3837 P07711 Cathepsin L 91.00% 96.61%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 90.98% 97.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.92% 95.56%
CHEMBL255 P29275 Adenosine A2b receptor 89.45% 98.59%
CHEMBL2443 P49862 Kallikrein 7 88.48% 94.00%
CHEMBL1949 P62937 Cyclophilin A 88.45% 98.57%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.19% 90.71%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 87.18% 96.00%
CHEMBL222 P23975 Norepinephrine transporter 85.99% 96.06%
CHEMBL1293249 Q13887 Kruppel-like factor 5 85.78% 86.33%
CHEMBL3401 O75469 Pregnane X receptor 85.13% 94.73%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 84.98% 91.71%
CHEMBL344 Q99705 Melanin-concentrating hormone receptor 1 84.65% 92.50%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 83.59% 96.47%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 83.49% 86.92%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 83.08% 96.90%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 83.06% 85.14%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.61% 95.89%
CHEMBL2996 Q05655 Protein kinase C delta 82.52% 97.79%
CHEMBL3060 Q9Y345 Glycine transporter 2 82.41% 99.17%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 82.02% 95.50%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 81.20% 82.86%
CHEMBL4530 P00488 Coagulation factor XIII 81.14% 96.00%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 81.07% 97.29%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 80.81% 85.00%
CHEMBL3492 P49721 Proteasome Macropain subunit 80.32% 90.24%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 139589859
LOTUS LTS0084288
wikiData Q104932944