Tsitsikammamine A

Details

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Internal ID 5cc09dd8-089a-4d06-8c16-01f9738074f2
Taxonomy Organoheterocyclic compounds > Quinolines and derivatives > Pyrroloquinolines > Pyrrolo[4,3,2-de]quinolines
IUPAC Name 3-(4-hydroxyphenyl)-5,9,14-triazatetracyclo[6.6.1.02,6.011,15]pentadeca-1(14),2(6),3,8(15),10-pentaen-7-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C18H13N3O2/c22-11-3-1-9(2-4-11)12-8-21-17-14(12)15-13-10(5-6-19-15)7-20-16(13)18(17)23/h1-4,7-8,20-22H,5-6H2
InChI Key YEAXSAGTEKAYBH-UHFFFAOYSA-N
Popularity 10 references in papers

Physical and Chemical Properties

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Molecular Formula C18H13N3O2
Molecular Weight 303.30 g/mol
Exact Mass 303.100776666 g/mol
Topological Polar Surface Area (TPSA) 81.20 Ų
XlogP 2.30

Synonyms

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CHEMBL457826

2D Structure

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2D Structure of Tsitsikammamine A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 96.69% 98.95%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 95.44% 95.64%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 91.33% 93.10%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.68% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.50% 99.23%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.28% 96.09%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 89.05% 96.21%
CHEMBL242 Q92731 Estrogen receptor beta 88.69% 98.35%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.50% 89.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.14% 93.03%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 86.14% 94.00%
CHEMBL3038469 P24941 CDK2/Cyclin A 86.08% 91.38%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 85.56% 91.71%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 85.32% 91.11%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 84.08% 95.78%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 83.60% 96.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.42% 94.45%
CHEMBL1937 Q92769 Histone deacetylase 2 83.40% 94.75%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 83.25% 96.09%
CHEMBL2208 P49137 MAP kinase-activated protein kinase 2 83.00% 95.20%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 82.48% 93.40%
CHEMBL5443 O00311 Cell division cycle 7-related protein kinase 82.40% 96.11%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 82.10% 99.15%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 81.57% 91.79%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.22% 90.71%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 135503612
LOTUS LTS0094861
wikiData Q105347126