Truncatone B

Details

Top
Internal ID 21d94a0f-b641-4015-9f92-0959502eacf5
Taxonomy Lignans, neolignans and related compounds
IUPAC Name (11S)-7,11,15-trihydroxypentacyclo[10.7.1.02,11.03,8.016,20]icosa-1,3(8),4,6,12(20),13,15-heptaene-9,17-dione
SMILES (Canonical) C1CC(=O)C2=C(C=CC3=C2C1=C4C3(CC(=O)C5=C4C=CC=C5O)O)O
SMILES (Isomeric) C1CC(=O)C2=C(C=CC3=C2C1=C4[C@@]3(CC(=O)C5=C4C=CC=C5O)O)O
InChI InChI=1S/C20H14O5/c21-12-3-1-2-9-17(12)15(24)8-20(25)11-5-7-14(23)18-13(22)6-4-10(16(11)18)19(9)20/h1-3,5,7,21,23,25H,4,6,8H2/t20-/m0/s1
InChI Key SKSDIVKAMYSIIU-FQEVSTJZSA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C20H14O5
Molecular Weight 334.30 g/mol
Exact Mass 334.08412354 g/mol
Topological Polar Surface Area (TPSA) 94.80 Ų
XlogP 1.80

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Truncatone B

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.22% 91.11%
CHEMBL1951 P21397 Monoamine oxidase A 97.99% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.97% 95.56%
CHEMBL2581 P07339 Cathepsin D 93.25% 98.95%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 91.49% 99.15%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 89.63% 82.69%
CHEMBL1937 Q92769 Histone deacetylase 2 88.98% 94.75%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.52% 99.23%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.56% 93.03%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 82.08% 96.67%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.63% 86.33%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 81.29% 96.09%
CHEMBL1929 P47989 Xanthine dehydrogenase 80.95% 96.12%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.82% 100.00%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 132546450
LOTUS LTS0071231
wikiData Q75063457