Triptohypol B

Details

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Internal ID 2a89038c-3d7f-4636-808d-a01d3e7cd3c2
Taxonomy Benzenoids > Phenanthrenes and derivatives
IUPAC Name (2R,4aS,6aR,6aS,14aS,14bR)-11-hydroxy-10-methoxy-2,4a,6a,6a,9,14a-hexamethyl-8-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H40O5/c1-17-23-18(14-20(32)24(17)35-7)28(4)11-13-30(6)22-16-27(3,25(33)34)9-8-26(22,2)10-12-29(30,5)21(28)15-19(23)31/h14-15,22,32H,8-13,16H2,1-7H3,(H,33,34)/t22-,26-,27-,28+,29-,30+/m1/s1
InChI Key KFGGKCFEQGLWFO-NLVUKCNFSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C30H40O5
Molecular Weight 480.60 g/mol
Exact Mass 480.28757437 g/mol
Topological Polar Surface Area (TPSA) 83.80 Ų
XlogP 6.90

Synonyms

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198129-84-9
(-)-Triptohypol B
CHEBI:132338
DTXSID901106787
(2R,4aS,6aS,12bR,14aS,14bR)-11-hydroxy-10-methoxy-2,4a,6a,9,12b,14a-hexamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid
Q27225541
24,25,26-Trinoroleana-1,3,5(10),7-tetraen-29-oic acid, 2-hydroxy-3-methoxy-9,13-dimethyl-6-oxo-, (9I(2),13I+/-,14I(2),20I+/-)-

2D Structure

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2D Structure of Triptohypol B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.91% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.96% 91.11%
CHEMBL3192 Q9BY41 Histone deacetylase 8 92.58% 93.99%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.55% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.02% 99.23%
CHEMBL241 Q14432 Phosphodiesterase 3A 88.88% 92.94%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 88.15% 94.78%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 88.14% 96.38%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 88.10% 99.15%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.64% 96.09%
CHEMBL340 P08684 Cytochrome P450 3A4 87.42% 91.19%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 87.29% 91.07%
CHEMBL279 P35968 Vascular endothelial growth factor receptor 2 87.12% 95.52%
CHEMBL4208 P20618 Proteasome component C5 86.80% 90.00%
CHEMBL1937 Q92769 Histone deacetylase 2 86.42% 94.75%
CHEMBL2581 P07339 Cathepsin D 85.34% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.53% 86.33%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 82.70% 82.38%
CHEMBL2535 P11166 Glucose transporter 82.45% 98.75%
CHEMBL211 P08172 Muscarinic acetylcholine receptor M2 80.81% 94.97%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.71% 93.03%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.28% 95.50%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 80.11% 91.79%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Tripterygium doianum

Cross-Links

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PubChem 101936044
LOTUS LTS0078460
wikiData Q27225541