Trichoverrin A

Details

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Internal ID a17872dc-fad4-4588-a15e-18b120786abe
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Sesquiterpenoids > Trichothecenes
IUPAC Name [(1S,2R,7R,11R,12S)-2-[[(E)-5-hydroxy-3-methylpent-2-enoyl]oxymethyl]-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-11-yl] (2Z,4E,6S,7S)-6,7-dihydroxyocta-2,4-dienoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H40O9/c1-18-9-11-28(16-35-26(34)14-19(2)10-12-30)23(13-18)37-24-15-22(27(28,4)29(24)17-36-29)38-25(33)8-6-5-7-21(32)20(3)31/h5-8,13-14,20-24,30-32H,9-12,15-17H2,1-4H3/b7-5+,8-6-,19-14+/t20-,21-,22+,23+,24?,27+,28+,29-/m0/s1
InChI Key SYKUAMFXVHJZSH-DHULOTLBSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C29H40O9
Molecular Weight 532.60 g/mol
Exact Mass 532.26723285 g/mol
Topological Polar Surface Area (TPSA) 135.00 Ų
XlogP 1.80

Synonyms

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F7HOM1M1LM
UNII-F7HOM1M1LM
76739-70-3
Trichothec-9-ene-4,15-diol, 12,13-epoxy-, 4-((2Z,4E,6S,7S)-6,7-dihydroxy-2,4-octadienoate) 15-((2E)-5-hydroxy-3-methyl-2-pentenoate), (4beta)-
CHEMBL136053
TRICHOTHEC-9-ENE-4,15-DIOL, 12,13-EPOXY-, 4-((2Z,4E,6S,7S)-6,7-DIHYDROXY-2,4-OCTADIENOATE) 15-((2E)-5-HYDROXY-3-METHYL-2-PENTENOATE), (4.BETA.)-

2D Structure

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2D Structure of Trichoverrin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.72% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.31% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.23% 97.25%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.65% 94.45%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.11% 86.33%
CHEMBL2581 P07339 Cathepsin D 90.39% 98.95%
CHEMBL4040 P28482 MAP kinase ERK2 90.18% 83.82%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.13% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.09% 97.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.87% 89.00%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 88.07% 91.07%
CHEMBL230 P35354 Cyclooxygenase-2 87.41% 89.63%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 86.64% 80.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 86.55% 95.50%
CHEMBL4227 P25090 Lipoxin A4 receptor 84.27% 100.00%
CHEMBL2996 Q05655 Protein kinase C delta 83.80% 97.79%
CHEMBL5028 O14672 ADAM10 82.69% 97.50%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.36% 97.14%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.90% 99.17%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 81.53% 98.75%
CHEMBL3401 O75469 Pregnane X receptor 80.93% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 73354304
LOTUS LTS0129158
wikiData Q105263629