Trichotoxin B

Details

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Internal ID daad02ad-b8a2-4b58-8da4-e6dd88d8c8cc
Taxonomy Organic oxygen compounds > Organooxygen compounds > Alcohols and polyols > Secondary alcohols
IUPAC Name (4R,5E,7S,10Z)-10-(chloromethylidene)-5,7-dimethylheptadeca-1,5-dien-16-yn-4-ol
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H31ClO/c1-5-7-8-9-10-12-19(16-21)14-13-17(3)15-18(4)20(22)11-6-2/h1,6,15-17,20,22H,2,7-14H2,3-4H3/b18-15+,19-16-/t17-,20+/m0/s1
InChI Key WKRSVZWXGDTWNJ-UELXYIEESA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C20H31ClO
Molecular Weight 322.90 g/mol
Exact Mass 322.2063433 g/mol
Topological Polar Surface Area (TPSA) 20.20 Ų
XlogP 7.10

Synonyms

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DTXSID001186914

2D Structure

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2D Structure of Trichotoxin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL242 Q92731 Estrogen receptor beta 94.61% 98.35%
CHEMBL1829 O15379 Histone deacetylase 3 92.96% 95.00%
CHEMBL1951 P21397 Monoamine oxidase A 92.35% 91.49%
CHEMBL221 P23219 Cyclooxygenase-1 91.66% 90.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.65% 91.11%
CHEMBL2581 P07339 Cathepsin D 90.89% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.62% 96.09%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.14% 99.17%
CHEMBL2885 P07451 Carbonic anhydrase III 89.79% 87.45%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 89.54% 89.34%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 88.08% 92.29%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 88.07% 95.17%
CHEMBL2996 Q05655 Protein kinase C delta 87.87% 97.79%
CHEMBL240 Q12809 HERG 87.86% 89.76%
CHEMBL203 P00533 Epidermal growth factor receptor erbB1 87.34% 97.34%
CHEMBL2039 P27338 Monoamine oxidase B 87.29% 92.51%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 86.32% 92.86%
CHEMBL3401 O75469 Pregnane X receptor 86.24% 94.73%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 85.66% 97.29%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 85.46% 98.75%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 83.18% 93.10%
CHEMBL206 P03372 Estrogen receptor alpha 82.86% 97.64%
CHEMBL3837 P07711 Cathepsin L 82.32% 96.61%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.43% 93.56%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.43% 95.89%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.33% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132851225
LOTUS LTS0196005
wikiData Q105307657