Trichostatin D

Details

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Internal ID 69ea1bc2-3f94-4c72-8859-654a3129c50d
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Phenylketones > Alkyl-phenylketones
IUPAC Name (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
SMILES (Canonical) CC(C=C(C)C=CC(=O)NOC1C(C(C(C(O1)CO)O)O)O)C(=O)C2=CC=C(C=C2)N(C)C
SMILES (Isomeric) C[C@H](/C=C(\C)/C=C/C(=O)NO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C(=O)C2=CC=C(C=C2)N(C)C
InChI InChI=1S/C23H32N2O8/c1-13(11-14(2)19(28)15-6-8-16(9-7-15)25(3)4)5-10-18(27)24-33-23-22(31)21(30)20(29)17(12-26)32-23/h5-11,14,17,20-23,26,29-31H,12H2,1-4H3,(H,24,27)/b10-5+,13-11+/t14-,17-,20-,21+,22-,23-/m1/s1
InChI Key YECWTLGLNDDPGE-YPBJGXFISA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C23H32N2O8
Molecular Weight 464.50 g/mol
Exact Mass 464.21586598 g/mol
Topological Polar Surface Area (TPSA) 149.00 Ų
XlogP 1.70

Synonyms

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CHEBI:39160
1-O-({(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoyl}amino)-alpha-D-glucopyranose
CHEMBL3353923
Q27119760
(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide

2D Structure

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2D Structure of Trichostatin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.44% 96.09%
CHEMBL3401 O75469 Pregnane X receptor 95.78% 94.73%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.40% 91.11%
CHEMBL3060 Q9Y345 Glycine transporter 2 95.13% 99.17%
CHEMBL2581 P07339 Cathepsin D 92.98% 98.95%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 89.99% 89.34%
CHEMBL4040 P28482 MAP kinase ERK2 88.89% 83.82%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 86.59% 96.00%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 85.38% 89.67%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 85.04% 100.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.18% 86.33%
CHEMBL5678 P34947 G protein-coupled receptor kinase 5 84.07% 88.00%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 84.07% 95.83%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.35% 90.71%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.53% 95.56%
CHEMBL3437 Q16853 Amine oxidase, copper containing 82.41% 94.00%
CHEMBL1293316 Q9HBX9 Relaxin receptor 1 82.34% 82.50%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.09% 89.00%
CHEMBL2716 Q8WUI4 Histone deacetylase 7 82.03% 89.44%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.94% 94.33%
CHEMBL1287628 Q9Y5S8 NADPH oxidase 1 81.23% 95.48%
CHEMBL2514 O95665 Neurotensin receptor 2 80.48% 100.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.44% 95.89%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.42% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 9847263
LOTUS LTS0130701
wikiData Q27119760