Tricholide B

Details

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Internal ID b70a09bc-2b96-46fb-aeea-1883dc339987
Taxonomy Phenylpropanoids and polyketides > Macrolide lactams
IUPAC Name (3E,12S,15S)-12-[(2R)-hexan-2-yl]-8-methoxy-3,5-dimethyl-13-oxa-1-azabicyclo[13.3.0]octadec-3-ene-2,14-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H43NO4/c1-6-7-10-19(3)23-13-8-11-21(29-5)15-14-18(2)17-20(4)24(27)26-16-9-12-22(26)25(28)30-23/h17-19,21-23H,6-16H2,1-5H3/b20-17+/t18?,19-,21?,22+,23+/m1/s1
InChI Key XWYPACJKLTZIII-OXDMWNTHSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C25H43NO4
Molecular Weight 421.60 g/mol
Exact Mass 421.31920885 g/mol
Topological Polar Surface Area (TPSA) 55.80 Ų
XlogP 6.00

Synonyms

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DTXSID701319534

2D Structure

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2D Structure of Tricholide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.99% 98.95%
CHEMBL1902 P62942 FK506-binding protein 1A 96.66% 97.05%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.32% 97.25%
CHEMBL5608 Q16288 NT-3 growth factor receptor 92.58% 95.89%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.41% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.41% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.25% 94.45%
CHEMBL1907 P15144 Aminopeptidase N 90.87% 93.31%
CHEMBL5103 Q969S8 Histone deacetylase 10 90.46% 90.08%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.54% 97.09%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 87.85% 100.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.73% 93.56%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 87.58% 82.38%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.31% 90.71%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.23% 96.47%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 85.75% 91.81%
CHEMBL1978 P11511 Cytochrome P450 19A1 85.05% 91.76%
CHEMBL5203 P33316 dUTP pyrophosphatase 84.98% 99.18%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 84.26% 98.33%
CHEMBL1871 P10275 Androgen Receptor 84.05% 96.43%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.96% 99.23%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 83.43% 94.80%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.01% 93.03%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 82.84% 86.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.24% 97.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.80% 86.33%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 80.75% 95.34%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.23% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139590495
LOTUS LTS0193966
wikiData Q105343879