Trichoderone A

Details

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Internal ID 5dbbe04c-7fdb-4d99-abab-d3cde4e32138
Taxonomy Organoheterocyclic compounds > Azaspirodecane derivatives
IUPAC Name (1S,10S,13R,16R,17S,18R)-1,5,18-trimethyl-16-(2-methylpropyl)-19-oxa-15-azapentacyclo[14.2.1.03,13.04,10.013,17]nonadeca-2,4-diene-12,14-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C24H33NO3/c1-13(2)11-23-20-15(4)22(5,28-23)12-17-19-14(3)8-6-7-9-16(19)10-18(26)24(17,20)21(27)25-23/h12-13,15-16,20H,6-11H2,1-5H3,(H,25,27)/t15-,16+,20-,22-,23-,24-/m1/s1
InChI Key CFVDPKHKEWPBHC-JDYAXKMBSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C24H33NO3
Molecular Weight 383.50 g/mol
Exact Mass 383.24604391 g/mol
Topological Polar Surface Area (TPSA) 55.40 Ų
XlogP 3.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Trichoderone A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.27% 98.95%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 94.40% 93.04%
CHEMBL325 Q13547 Histone deacetylase 1 93.66% 95.92%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.93% 97.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.78% 91.11%
CHEMBL1937 Q92769 Histone deacetylase 2 92.48% 94.75%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.79% 94.45%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 91.70% 94.80%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.69% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.40% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.02% 99.23%
CHEMBL3192 Q9BY41 Histone deacetylase 8 88.38% 93.99%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 88.10% 95.34%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.94% 90.71%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 87.43% 93.40%
CHEMBL5103 Q969S8 Histone deacetylase 10 87.21% 90.08%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 87.07% 85.11%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.71% 95.89%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.23% 95.56%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 85.09% 95.71%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.73% 100.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.48% 93.56%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.31% 94.00%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 82.67% 89.05%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.44% 86.33%
CHEMBL3310 Q96DB2 Histone deacetylase 11 80.74% 88.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 80.62% 85.14%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 80.39% 92.88%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 57413333
LOTUS LTS0074945
wikiData Q77574182