Trenudine

Details

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Internal ID baee12a9-d9c8-48de-a1cc-283204781fad
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (1S,2S,4S,5R,6S,10S,11R,12E,14E)-20-chloro-10,24,25-trihydroxy-11,16,19-trimethoxy-2,5,15,25,28-pentamethyl-3,7,30-trioxa-9,22,27-triazapentacyclo[20.8.2.16,10.117,21.02,4]tetratriaconta-12,14,17(33),18,20-pentaene-8,26,29,32-tetrone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C36H48ClN3O13/c1-17-10-9-11-25(49-7)36(47)15-23(51-33(45)39-36)18(2)30-35(5,53-30)26-14-27(42)40(21-12-20(29(17)50-8)13-22(48-6)28(21)37)16-24(41)34(4,46)32(44)38-19(3)31(43)52-26/h9-13,18-19,23-26,29-30,41,46-47H,14-16H2,1-8H3,(H,38,44)(H,39,45)/b11-9+,17-10+/t18-,19?,23+,24?,25-,26+,29?,30+,34?,35+,36+/m1/s1
InChI Key SEGCAWMBEYYQNG-ASTJGFRCSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C36H48ClN3O13
Molecular Weight 766.20 g/mol
Exact Mass 765.2875663 g/mol
Topological Polar Surface Area (TPSA) 215.00 Ų
XlogP 0.90

Synonyms

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CHEMBL502969

2D Structure

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2D Structure of Trenudine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.34% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.92% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.03% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.25% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.11% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 95.07% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 93.60% 95.89%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.79% 94.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 91.27% 97.14%
CHEMBL3401 O75469 Pregnane X receptor 90.76% 94.73%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.18% 97.09%
CHEMBL4302 P08183 P-glycoprotein 1 88.42% 92.98%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 88.41% 96.90%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 87.44% 100.00%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 86.82% 97.31%
CHEMBL220 P22303 Acetylcholinesterase 86.07% 94.45%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 85.81% 89.05%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 84.83% 96.21%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 84.23% 91.03%
CHEMBL2581 P07339 Cathepsin D 82.30% 98.95%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.56% 95.89%
CHEMBL1871 P10275 Androgen Receptor 81.00% 96.43%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 80.83% 93.40%
CHEMBL340 P08684 Cytochrome P450 3A4 80.28% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Mallotus nudiflorus

Cross-Links

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PubChem 44559314
LOTUS LTS0188223
wikiData Q104397384