CID 135461157

Details

Top
Internal ID dfb0eaf5-e283-46ec-89d1-47236fa3da95
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Aminosaccharides > Aminoglycosides
IUPAC Name (2S,3S)-3-[(12S,19S,26E,29S)-5-[4-[(3-amino-3-oxoprop-1-en-2-yl)carbamoyl]-1,3-thiazol-2-yl]-4-hydroxy-29-[(1R)-1-hydroxyethyl]-12-(hydroxymethyl)-26-(1-methoxyethylidene)-14,21,28,31-tetraoxo-10,17,24,34-tetrathia-6,13,20,27,30,35,36,37,38-nonazahexacyclo[30.2.1.18,11.115,18.122,25.02,7]octatriaconta-1(35),2,4,6,8,11(38),15,18(37),22,25(36),32-undecaen-19-yl]-2-[(2S,4S,5R,6S)-5-(dimethylamino)-4-hydroxy-4,6-dimethyloxan-2-yl]oxy-3-hydroxypropanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C50H55N13O16S5/c1-17(38(51)68)52-39(69)24-14-83-47(57-24)33-28(66)9-21-32(59-33)23-12-81-45(54-23)22(11-64)53-40(70)25-15-84-48(58-25)34(35(67)36(49(74)75)79-29-10-50(5,76)37(63(6)7)20(4)78-29)62-42(72)27-16-82-46(56-27)31(19(3)77-8)61-43(73)30(18(2)65)60-41(71)26-13-80-44(21)55-26/h9,12-16,18,20,22,29-30,34-37,64-67,76H,1,10-11H2,2-8H3,(H2,51,68)(H,52,69)(H,53,70)(H,60,71)(H,61,73)(H,62,72)(H,74,75)/b31-19+/t18-,20+,22+,29+,30+,34+,35+,36+,37-,50+/m1/s1
InChI Key MVHBCLZSBYPNKG-NWUSPKIPSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C50H55N13O16S5
Molecular Weight 1254.40 g/mol
Exact Mass 1253.24932859 g/mol
Topological Polar Surface Area (TPSA) 577.00 Ų
XlogP -2.10

Synonyms

Top
CHEMBL554539
SCHEMBL14192137

2D Structure

Top
2D Structure of CID 135461157

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.66% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.50% 91.11%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 98.13% 93.03%
CHEMBL2581 P07339 Cathepsin D 97.32% 98.95%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 96.77% 96.21%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 95.68% 95.64%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.63% 94.45%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 93.86% 99.15%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.39% 99.23%
CHEMBL340 P08684 Cytochrome P450 3A4 92.13% 91.19%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.22% 86.33%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 91.16% 96.90%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 90.62% 94.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 89.99% 95.00%
CHEMBL3384 Q16512 Protein kinase N1 89.76% 80.71%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 89.30% 85.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.03% 97.09%
CHEMBL4208 P20618 Proteasome component C5 88.32% 90.00%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 88.29% 91.24%
CHEMBL1937 Q92769 Histone deacetylase 2 87.65% 94.75%
CHEMBL2996 Q05655 Protein kinase C delta 87.36% 97.79%
CHEMBL3060 Q9Y345 Glycine transporter 2 87.23% 99.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.60% 95.56%
CHEMBL261 P00915 Carbonic anhydrase I 86.58% 96.76%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 86.14% 85.14%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.44% 90.71%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.05% 92.62%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 82.70% 93.10%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.59% 89.00%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 82.49% 100.00%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 82.35% 97.50%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 81.65% 95.71%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.40% 95.89%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 81.38% 92.88%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 135461157
LOTUS LTS0074494
wikiData Q105173004