Tetroazolemycin B

Details

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Internal ID 9aec9706-7a69-47e7-973b-86cf63933212
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives
IUPAC Name (1S,6S)-9-[[(2S,4S)-2-[(4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-oxazol-4-yl]-3-methyl-1,3-thiazolidin-4-yl]methyl]-7-[[(2R,4S)-2-[(4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-oxazol-4-yl]-3-methyl-1,3-thiazolidin-4-yl]methyl]-3,4-dithia-7,9-diazabicyclo[4.2.2]decane-8,10-dione
SMILES (Canonical) CN1C(CSC1C2COC(=N2)C3=CC=CC=C3O)CN4C5CSSCC(C4=O)N(C5=O)CC6CSC(N6C)C7COC(=N7)C8=CC=CC=C8O
SMILES (Isomeric) CN1[C@H](CS[C@@H]1[C@@H]2COC(=N2)C3=CC=CC=C3O)CN4[C@@H]5CSSC[C@H](C4=O)N(C5=O)C[C@H]6CS[C@H](N6C)[C@@H]7COC(=N7)C8=CC=CC=C8O
InChI InChI=1S/C34H40N6O6S4/c1-37-19(15-47-33(37)23-13-45-29(35-23)21-7-3-5-9-27(21)41)11-39-25-17-49-50-18-26(31(39)43)40(32(25)44)12-20-16-48-34(38(20)2)24-14-46-30(36-24)22-8-4-6-10-28(22)42/h3-10,19-20,23-26,33-34,41-42H,11-18H2,1-2H3/t19-,20-,23-,24-,25+,26+,33-,34+/m0/s1
InChI Key PLNJNPILMFLHRV-NDEUFGCJSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C34H40N6O6S4
Molecular Weight 757.00 g/mol
Exact Mass 756.18921771 g/mol
Topological Polar Surface Area (TPSA) 232.00 Ų
XlogP 2.80

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Tetroazolemycin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.64% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.16% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.59% 96.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 92.70% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.23% 86.33%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.51% 85.14%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 87.50% 91.11%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 87.31% 93.40%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.33% 89.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 85.21% 82.69%
CHEMBL1978 P11511 Cytochrome P450 19A1 84.81% 91.76%
CHEMBL3401 O75469 Pregnane X receptor 82.15% 94.73%
CHEMBL4208 P20618 Proteasome component C5 81.81% 90.00%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 80.14% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139583989
LOTUS LTS0096606
wikiData Q75070253