Tenvermectin D

Details

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Internal ID 5ebb0ffa-d164-4364-83e0-bf026c4de99a
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues > Milbemycins
IUPAC Name (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21S,24S)-13-ethyl-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',6',11,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
SMILES (Canonical) CCC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)O)OC)OC)C)OC7(C4)CCC(C(O7)C)C)O
SMILES (Isomeric) CC[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)\C)O[C@]7(C4)CC[C@@H]([C@H](O7)C)C)O
InChI InChI=1S/C46H70O14/c1-10-30-12-11-13-31-23-53-43-39(47)26(4)18-34(46(31,43)50)44(49)56-33-19-32(60-45(22-33)17-16-24(2)27(5)59-45)15-14-25(3)41(30)57-38-21-36(52-9)42(29(7)55-38)58-37-20-35(51-8)40(48)28(6)54-37/h11-14,18,24,27-30,32-43,47-48,50H,10,15-17,19-23H2,1-9H3/b12-11+,25-14+,31-13+/t24-,27+,28-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39-,40-,41+,42-,43+,45-,46+/m0/s1
InChI Key LRRLXHFQOQAAEL-DJEUOMBCSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C46H70O14
Molecular Weight 847.00 g/mol
Exact Mass 846.47655690 g/mol
Topological Polar Surface Area (TPSA) 170.00 Ų
XlogP 3.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Tenvermectin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.79% 96.09%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 97.44% 96.77%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.40% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.12% 91.11%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.14% 86.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.13% 97.09%
CHEMBL1871 P10275 Androgen Receptor 92.47% 96.43%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.57% 94.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 90.37% 100.00%
CHEMBL226 P30542 Adenosine A1 receptor 90.15% 95.93%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 89.88% 96.95%
CHEMBL4072 P07858 Cathepsin B 89.04% 93.67%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 88.59% 97.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.35% 95.56%
CHEMBL255 P29275 Adenosine A2b receptor 87.05% 98.59%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 86.00% 92.62%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.87% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.18% 89.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.85% 94.45%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.63% 96.00%
CHEMBL3401 O75469 Pregnane X receptor 81.04% 94.73%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.89% 95.89%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 80.01% 97.21%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139591318
LOTUS LTS0057000
wikiData Q105156286