Teicoplanin A2-2

Details

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Internal ID 49acaf38-adbf-4a00-ba23-b8364c652b92
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name (1S,2R,19R,22R,34S,37R,40R,52S)-2-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-amino-5,15-dichloro-64-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(8-methylnonanoylamino)oxan-2-yl]oxy-26,31,44,49-tetrahydroxy-21,35,38,54,56,59-hexaoxo-47-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51]hexahexaconta-3,5,8,10,12(64),14,16,23(61),24,26,29(60),30,32,41(57),42,44,46(51),47,49,62,65-henicosaene-52-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C88H97Cl2N9O33/c1-33(2)8-6-4-5-7-9-60(108)94-68-74(113)71(110)58(31-101)129-87(68)132-78-55-25-40-26-56(78)126-52-17-13-38(23-47(52)90)77(131-86-67(92-34(3)103)73(112)70(109)57(30-100)128-86)69-84(121)98-66(85(122)123)45-28-42(105)29-54(127-88-76(115)75(114)72(111)59(32-102)130-88)61(45)44-22-37(12-14-49(44)106)63(81(118)99-69)96-83(120)65(40)97-82(119)64-39-20-41(104)27-43(21-39)124-53-24-36(11-15-50(53)107)62(91)80(117)93-48(79(116)95-64)19-35-10-16-51(125-55)46(89)18-35/h10-18,20-29,33,48,57-59,62-77,86-88,100-102,104-107,109-115H,4-9,19,30-32,91H2,1-3H3,(H,92,103)(H,93,117)(H,94,108)(H,95,116)(H,96,120)(H,97,119)(H,98,121)(H,99,118)(H,122,123)/t48-,57-,58-,59-,62-,63-,64+,65-,66+,67-,68-,69+,70-,71-,72-,73-,74-,75+,76+,77-,86+,87+,88+/m1/s1
InChI Key GHOXVFYORXUCPY-PKMGYIMSSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C88H97Cl2N9O33
Molecular Weight 1879.70 g/mol
Exact Mass 1877.5565820 g/mol
Topological Polar Surface Area (TPSA) 662.00 Ų
XlogP 0.30

Synonyms

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9V7Z6HDK93
CHEBI:85251
RefChem:1099424
Ristomycin A aglycone, 34-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxononyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-
(1S,2R,19R,22R,34S,37R,40R,52S)-2-((2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy-22-amino-5,15-dichloro-64-((2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(8-methylnonanoylamino)oxan-2-yl)oxy-26,31,44,49-tetrahydroxy-21,35,38,54,56,59-hexaoxo-47-((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo(38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51)hexahexaconta-3,5,8,10,12(64),14,16,23(61),24,26,29(60),30,32,41(57),42,44,46(51),47,49,62,65-henicosaene-52-carboxylic acid
Teichomycin A2 factor 2
91032-26-7
Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(8-methyl-1-oxononyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-
Teichomycin A2 -2
34-O-(2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((8-methyl-1-oxononyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Teicoplanin A2-2

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL220 P22303 Acetylcholinesterase 99.97% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.96% 91.11%
CHEMBL2581 P07339 Cathepsin D 99.90% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 99.38% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.90% 99.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.14% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 97.57% 97.09%
CHEMBL3359 P21462 Formyl peptide receptor 1 96.01% 93.56%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 95.68% 99.15%
CHEMBL3401 O75469 Pregnane X receptor 94.30% 94.73%
CHEMBL2413 P32246 C-C chemokine receptor type 1 94.12% 89.50%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 94.01% 92.29%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 93.83% 85.00%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 93.46% 89.62%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 93.36% 96.21%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 91.80% 95.50%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.70% 95.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 91.19% 90.71%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.18% 89.00%
CHEMBL2179 P04062 Beta-glucocerebrosidase 90.61% 85.31%
CHEMBL2535 P11166 Glucose transporter 89.48% 98.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.14% 95.89%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 87.33% 96.47%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 87.17% 97.23%
CHEMBL340 P08684 Cytochrome P450 3A4 87.01% 91.19%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 86.80% 100.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.56% 96.90%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 84.53% 97.21%
CHEMBL2996 Q05655 Protein kinase C delta 83.20% 97.79%
CHEMBL5255 O00206 Toll-like receptor 4 82.90% 92.50%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 82.63% 96.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.19% 86.33%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 82.05% 95.71%
CHEMBL218 P21554 Cannabinoid CB1 receptor 81.68% 96.61%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.61% 96.00%
CHEMBL236 P41143 Delta opioid receptor 81.22% 99.35%
CHEMBL4208 P20618 Proteasome component C5 80.51% 90.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 80.36% 92.88%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 16198036
LOTUS LTS0078345
wikiData Q27158435