Taxumairol O

Details

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Internal ID 4ff49e2e-0630-4c81-bc9f-27d188fc8900
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Taxanes and derivatives
IUPAC Name [(1S,2S,3R,4S,5S,7S,8S,9R,10R,13S)-9,10,13-triacetyloxy-1,2,4,5-tetrahydroxy-4-(hydroxymethyl)-8,12,15,15-tetramethyl-7-tricyclo[9.3.1.03,8]pentadec-11-enyl] acetate
SMILES (Canonical) CC1=C2C(C(C3(C(CC(C(C3C(C(C2(C)C)(CC1OC(=O)C)O)O)(CO)O)O)OC(=O)C)C)OC(=O)C)OC(=O)C
SMILES (Isomeric) CC1=C2[C@H]([C@@H]([C@@]3([C@H](C[C@@H]([C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)C)O)O)(CO)O)O)OC(=O)C)C)OC(=O)C)OC(=O)C
InChI InChI=1S/C28H42O13/c1-12-17(38-13(2)30)10-28(37)23(35)22-26(8,19(39-14(3)31)9-18(34)27(22,36)11-29)24(41-16(5)33)21(40-15(4)32)20(12)25(28,6)7/h17-19,21-24,29,34-37H,9-11H2,1-8H3/t17-,18-,19-,21+,22-,23-,24-,26+,27-,28+/m0/s1
InChI Key UKTPGJFEWDPYOU-CDGZCQTISA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C28H42O13
Molecular Weight 586.60 g/mol
Exact Mass 586.26254139 g/mol
Topological Polar Surface Area (TPSA) 206.00 Ų
XlogP -1.00

Synonyms

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SCHEMBL44470
[(1S,2S,3R,4S,5S,7S,8S,9R,10R,13S)-9,10,13-Triacetyloxy-1,2,4,5-tetrahydroxy-4-(hydroxymethyl)-8,12,15,15-tetramethyl-7-tricyclo[9.3.1.03,8]pentadec-11-enyl] acetate

2D Structure

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2D Structure of Taxumairol O

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.59% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.75% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.71% 91.11%
CHEMBL2581 P07339 Cathepsin D 92.45% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.00% 85.14%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 90.97% 96.95%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 87.09% 95.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.93% 97.09%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 86.08% 95.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.37% 94.45%
CHEMBL340 P08684 Cytochrome P450 3A4 85.13% 91.19%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 84.27% 94.33%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.14% 86.33%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 82.35% 96.90%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.83% 89.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.86% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Taxus mairei

Cross-Links

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PubChem 10674857
LOTUS LTS0093570
wikiData Q105274893