Takakiamide

Details

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Internal ID 9bc57e36-002b-4ba1-ad4c-88430bddd0ae
Taxonomy Organoheterocyclic compounds > Benzodiazepines > 1,4-benzodiazepines
IUPAC Name 3-[[1-(3-methylbut-2-enyl)indol-3-yl]methyl]-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
SMILES (Canonical) CC(=CCN1C=C(C2=CC=CC=C21)CC3C(=O)NC4=CC=CC=C4C(=O)N3)C
SMILES (Isomeric) CC(=CCN1C=C(C2=CC=CC=C21)CC3C(=O)NC4=CC=CC=C4C(=O)N3)C
InChI InChI=1S/C23H23N3O2/c1-15(2)11-12-26-14-16(17-7-4-6-10-21(17)26)13-20-23(28)24-19-9-5-3-8-18(19)22(27)25-20/h3-11,14,20H,12-13H2,1-2H3,(H,24,28)(H,25,27)
InChI Key RLNXCRSSBIJUAB-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C23H23N3O2
Molecular Weight 373.40 g/mol
Exact Mass 373.17902698 g/mol
Topological Polar Surface Area (TPSA) 63.10 Ų
XlogP 3.80

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Takakiamide

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.12% 97.25%
CHEMBL1937 Q92769 Histone deacetylase 2 97.47% 94.75%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.29% 91.11%
CHEMBL5103 Q969S8 Histone deacetylase 10 96.77% 90.08%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.75% 96.09%
CHEMBL2581 P07339 Cathepsin D 96.72% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.40% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.11% 95.56%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 91.07% 82.69%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.58% 89.00%
CHEMBL255 P29275 Adenosine A2b receptor 88.25% 98.59%
CHEMBL3524 P56524 Histone deacetylase 4 87.27% 92.97%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.86% 99.23%
CHEMBL3310 Q96DB2 Histone deacetylase 11 85.53% 88.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.22% 86.33%
CHEMBL3401 O75469 Pregnane X receptor 82.96% 94.73%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.84% 92.62%
CHEMBL4237 O75582 Ribosomal protein S6 kinase alpha 5 81.44% 91.00%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 81.20% 95.83%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 80.78% 96.39%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 74833823
LOTUS LTS0069485
wikiData Q77498403