Swietmanin I

Details

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Internal ID 9eeedc3e-a4f6-4803-99ae-1a6898e53784
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Steroid lactones
IUPAC Name [(1R,2S,5R,6R,13R,14S,16S)-6-(furan-3-yl)-13-hydroxy-16-(2-methoxy-2-oxoethyl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.02,11.05,10]heptadeca-9,11-dien-14-yl] (E)-2-methylbut-2-enoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H38O9/c1-8-17(2)26(35)41-28-29(3,4)22(14-23(33)38-7)31(6)20-9-11-30(5)21(19(20)15-32(28,37)27(31)36)13-24(34)40-25(30)18-10-12-39-16-18/h8,10,12-13,15-16,20,22,25,28,37H,9,11,14H2,1-7H3/b17-8+/t20-,22-,25-,28-,30+,31+,32-/m0/s1
InChI Key SRTLWTGAXHUNEM-YEEVHOMBSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C32H38O9
Molecular Weight 566.60 g/mol
Exact Mass 566.25158279 g/mol
Topological Polar Surface Area (TPSA) 129.00 Ų
XlogP 3.50

Synonyms

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((1R,2S,5R,6R,13R,14S,16S)-6-(furan-3-yl)-13-hydroxy-16-(2-methoxy-2-oxoethyl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo(11.3.1.02,11.05,10)heptadeca-9,11-dien-14-yl) (E)-2-methylbut-2-enoate
[(1R,2S,5R,6R,13R,14S,16S)-6-(furan-3-yl)-13-hydroxy-16-(2-methoxy-2-oxoethyl)-1,5,15,15-tetramethyl-8,17-dioxo-7-oxatetracyclo[11.3.1.02,11.05,10]heptadeca-9,11-dien-14-yl] (E)-2-methylbut-2-enoate
RefChem:186912
1197347-52-6
CHEMBL1075776

2D Structure

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2D Structure of Swietmanin I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.42% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.34% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.17% 96.09%
CHEMBL3038469 P24941 CDK2/Cyclin A 92.35% 91.38%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 91.92% 91.24%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.56% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.97% 86.33%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 89.09% 94.80%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 89.00% 94.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.41% 95.89%
CHEMBL3524 P56524 Histone deacetylase 4 88.22% 92.97%
CHEMBL1994 P08235 Mineralocorticoid receptor 87.84% 100.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.60% 99.23%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 85.49% 86.92%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 84.94% 91.07%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.24% 92.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.80% 95.56%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 82.45% 95.71%
CHEMBL221 P23219 Cyclooxygenase-1 81.62% 90.17%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 80.33% 80.00%
CHEMBL4208 P20618 Proteasome component C5 80.06% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Swietenia mahagoni

Cross-Links

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PubChem 44613656
LOTUS LTS0180464
wikiData Q105259408