Svetamycin F

Details

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Internal ID 16fce7ed-7842-4bc0-862f-be0acc2db68c
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3R,5S,10S,13S,14S,15R,23S,26S)-5-bromo-14,15-dihydroxy-23-(hydroxymethyl)-10,23-dimethyl-21-oxa-1,7,8,11,17,18,24,30-octazatetracyclo[24.4.0.03,8.013,18]triacont-16-ene-2,9,12,19,22,25-hexone
SMILES (Canonical) CC1C(=O)N2C(CC(CN2)Br)C(=O)N3C(CCCN3)C(=O)NC(C(=O)OCC(=O)N4C(C(C(C=N4)O)O)C(=O)N1)(C)CO
SMILES (Isomeric) C[C@H]1C(=O)N2[C@H](C[C@@H](CN2)Br)C(=O)N3[C@@H](CCCN3)C(=O)N[C@@](C(=O)OCC(=O)N4[C@@H]([C@@H]([C@@H](C=N4)O)O)C(=O)N1)(C)CO
InChI InChI=1S/C24H35BrN8O10/c1-11-21(40)32-14(6-12(25)7-27-32)22(41)31-13(4-3-5-26-31)19(38)30-24(2,10-34)23(42)43-9-16(36)33-17(20(39)29-11)18(37)15(35)8-28-33/h8,11-15,17-18,26-27,34-35,37H,3-7,9-10H2,1-2H3,(H,29,39)(H,30,38)/t11-,12-,13-,14+,15+,17-,18+,24-/m0/s1
InChI Key RRYAXJUCQNEXSG-WECLKIJSSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C24H35BrN8O10
Molecular Weight 675.50 g/mol
Exact Mass 674.16595 g/mol
Topological Polar Surface Area (TPSA) 243.00 Ų
XlogP -2.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Svetamycin F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3137262 O60341 LSD1/CoREST complex 97.00% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.82% 96.09%
CHEMBL2581 P07339 Cathepsin D 94.36% 98.95%
CHEMBL5103 Q969S8 Histone deacetylase 10 90.85% 90.08%
CHEMBL1994 P08235 Mineralocorticoid receptor 89.84% 100.00%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 89.49% 96.77%
CHEMBL228 P31645 Serotonin transporter 89.06% 95.51%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.99% 99.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.62% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.42% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.99% 97.25%
CHEMBL1902 P62942 FK506-binding protein 1A 86.95% 97.05%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.95% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.59% 86.33%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.79% 94.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.61% 94.45%
CHEMBL3310 Q96DB2 Histone deacetylase 11 82.74% 88.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.13% 93.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.87% 90.71%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.86% 85.14%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 81.53% 93.04%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.32% 89.00%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 81.10% 86.00%
CHEMBL2140 P48775 Tryptophan 2,3-dioxygenase 80.55% 98.46%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139591397
LOTUS LTS0071737
wikiData Q105244431