Sulfamethizole

Details

• Internal ID: 17a83349-4bd3-4abc-8d58-eb95e0ade944
• Taxonomy: Benzenoids > Benzene and substituted derivatives > Benzenesulfonamides > Aminobenzenesulfonamides
• IUPAC Name: 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
• InChI: InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)
• InChI Key: VACCAVUAMIDAGB-UHFFFAOYSA-N
• Popularity: 894 references in papers

Physical and Chemical Properties

• Molecular Formula: C₉H₁₀N₄O₂S₂
• Molecular Weight: 270.30 g/mol
• Exact Mass: 270.02451792 g/mol
• Topological Polar Surface Area (TPSA): 135.00 Ų
• XlogP: 0.50

Synonyms

• 144-82-1
• Sulfamethizol
• Sulphamethizole
• Thiosulfil
• Rufol
• Proklar
• Sulfamethylthiadiazole
• 4-Amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
• Sulfamethizolum
• Sulfametizol
• Sulfurine
• Ayerlucil
• Methazol
• Microsul
• Sulfapyelon
• Sulfstat
• Tetracid
• Thidicur
• Ultrasul
• Urocydal
• Urodiaton
• Urolucosil
• Urosulfin
• Lucosil
• Renasul
• Salimol
• Famet
• Uroz
• Sulfa gram
• Solfametizolo
• Sulfametizol [INN-Spanish]
• Sulfamethizolum [INN-Latin]
• 4-Amino-N-(5-Methyl-1,3,4-Thiadiazol-2-Yl)Benzene-1-Sulfonamide
• RP 2145
• Benzenesulfonamide, 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)-
• VK 53
• CCRIS 756
• sulphamethazole
• CHEBI:9331
• sulphamethiozole
• Sulfamethizole (Proklar)
• HSDB 4379
• 2-(p-Aminobenzenesulfonamido)-5-methylthiadiazole
• EINECS 205-641-1
• 2-Methyl-5-sulfanilamido-1,3,4-thiadiazole
• 2-Sulfanilamido-5-methyl-1,3,4-thiadiazole
• 5-Methyl-2-sulfanilamido-1,3,4-thiadiazole
• NSC-757327
• DTXSID5023615
• N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide
• AI3-50149
• UNII-25W8454H16
• N(sup 1)-(5-Methyl-1,3,4-thiadiazol-2-yl)-sulfanilamide
• CHEMBL1191
• MLS000028603
• DTXCID803615
• N(sup 1)-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide
• 25W8454H16
• Solfametizolo [DCIT]
• Sulfamethizole [USP:INN:BAN:JAN]
• N(1)-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide
• NSC 757327
• NCGC00016407-05
• NCGC00016407-08
• CAS-144-82-1
• SMR000058666
• Sulfanilamide, N(sup 1)-(5-methyl-1,3,4-thiadiazol-2-yl)-
• Sulfametizol (INN-Spanish)
• Sulfamethizolum (INN-Latin)
• Thiosulfil-A-Forte
• SULFAMETHIZOLE (MART.)
• SULFAMETHIZOLE [MART.]
• SULFAMETHIZOLE (USP-RS)
• SULFAMETHIZOLE [USP-RS]
• SULFAMETHIZOLE (EP IMPURITY)
• Sulfamethizole (USP:INN:BAN:JAN)
• SULFAMETHIZOLE [EP IMPURITY]
• N (SUP 1)-(5-METHYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDE
• SULFAMETHIZOLE (EP MONOGRAPH)
• SULFAMETHIZOLE [EP MONOGRAPH]
• SULFAMETHIZOLE (USP MONOGRAPH)
• SULFAMETHIZOLE [USP MONOGRAPH]
• Thiosulfil (TN)
• SR-01000003158
• sulfametizolo
• Prestwick_114
• Spectrum_000992
• Opera_ID_1595
• Prestwick0_000742
• Prestwick1_000742
• Prestwick2_000742
• Prestwick3_000742
• Spectrum2_001322
• Spectrum3_000570
• Spectrum4_000640
• Spectrum5_001078
• Epitope ID:122233
• SULFAMETHIZOLE [MI]
• SULFAMETHIZOLE [INN]
• SULFAMETHIZOLE [JAN]
• SCHEMBL26453
• BSPBio_000724
• BSPBio_001960
• KBioGR_001260
• KBioSS_001472
• SULFAMETHIZOLE [HSDB]
• MLS002303066
• DivK1c_000141
• SPECTRUM1500549
• SULFAMETHIZOLE [VANDF]
• SPBio_001443
• SPBio_002663
• Sulfamethizole-(phenyl-13C6)
• BPBio1_000798
• SULFAMETHIZOLE [WHO-DD]
• GTPL12683
• HMS500H03
• KBio1_000141
• KBio2_001472
• KBio2_004040
• KBio2_006608
• KBio3_001460
• B05CA04
• D06BA04
• J01EB02
• S01AB01
• NINDS_000141
• Sulfamethizole (JP17/USP/INN)
• HMS1570E06
• HMS1921A19
• HMS2092I21
• HMS2097E06
• HMS2233L09
• HMS3371A13
• HMS3655F05
• HMS3714E06
• Pharmakon1600-01500549
• HY-B0333
• SULFAMETHIZOLE [ORANGE BOOK]
• Tox21_110425
• Tox21_201035
• BDBM50295558
• CCG-39260
• MFCD00053363
• NSC757327
• s1957
• AKOS002666345
• Tox21_110425_1
• DB00576
• IDI1_000141
• SMP1_000284
• NCGC00016407-01
• NCGC00016407-02
• NCGC00016407-03
• NCGC00016407-04
• NCGC00016407-06
• NCGC00016407-07
• NCGC00016407-09
• NCGC00016407-11
• NCGC00016407-13
• NCGC00024107-03
• NCGC00024107-04
• NCGC00024107-05
• NCGC00258588-01
• AS-10177
• SBI-0051523.P003
• AB00052098
• SW196425-3
• Sulfamethizol 1000 microg/mL in Acetonitrile
• 4-(AMINOMETHYL)-1-N-BOC-PIPERIDINE-HCl
• C08050
• D00870
• D88000
• EN300-217740
• AB00052098_15
• AB00052098_16
• A921093
• Sulfamethizole, VETRANAL(TM), analytical standard
• J-008011
• Q3976824
• SR-01000003158-2
• SR-01000003158-3
• Sulfamethizole, analytical standard, >=99% (HPLC)
• BRD-K31682896-001-05-9
• BRD-K31682896-001-15-8
• Sulfamethizole, European Pharmacopoeia (EP) Reference Standard
• 4-amino-N-(5-methyl[1,3,4]thiadiazol-2-yl)-benzenesulfonamide
• N(SUP1)-(5-METHYL-1,3,4-THIADIAZOL-2-YL)SULFANILIMIDE
• Sulfamethizole, United States Pharmacopeia (USP) Reference Standard
• SULFANILAMIDE, N(1)-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-
• 4-AMINO-N-(5-METHYL-1,3,4-THIADIAZOL-2-YL)BENZENESULFONIMIDE

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL5932	P53671	LIM domain kinase 2	96.04%	96.49%
CHEMBL3108638	O15164	Transcription intermediary factor 1-alpha	95.95%	95.56%
CHEMBL3401	O75469	Pregnane X receptor	95.49%	94.73%
CHEMBL5163	Q9NY46	Sodium channel protein type III alpha subunit	93.99%	96.90%
CHEMBL1952	P04818	Thymidylate synthase	92.17%	93.53%
CHEMBL4224	P49759	Dual specificty protein kinase CLK1	91.93%	85.30%
CHEMBL1075094	Q16236	Nuclear factor erythroid 2-related factor 2	89.55%	96.00%
CHEMBL5409	Q8TDU6	G-protein coupled bile acid receptor 1	87.71%	93.65%
CHEMBL3055	P50613	Cyclin-dependent kinase 7	85.69%	81.88%
CHEMBL2093869	P05106	Integrin alpha-IIb/beta-3	85.51%	95.42%
CHEMBL4040	P28482	MAP kinase ERK2	85.38%	83.82%
CHEMBL3267	P48736	PI3-kinase p110-gamma subunit	84.98%	95.71%
CHEMBL1293277	O15118	Niemann-Pick C1 protein	84.81%	81.11%
CHEMBL1287628	Q9Y5S8	NADPH oxidase 1	84.64%	95.48%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	84.50%	96.09%
CHEMBL2378	P30307	Dual specificity phosphatase Cdc25C	84.29%	96.67%
CHEMBL255	P29275	Adenosine A2b receptor	84.17%	98.59%
CHEMBL226	P30542	Adenosine A1 receptor	84.00%	95.93%
CHEMBL2635	P51452	Dual specificity protein phosphatase 3	82.37%	94.00%
CHEMBL3359	P21462	Formyl peptide receptor 1	81.01%	93.56%

Plants that contains it

There are no matching plants.

Cross-Links

• PubChem: 5328
• LOTUS: LTS0210309
• wikiData: Q3976824