Strebloside

Details

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Internal ID c26c32e2-1cca-47aa-b14d-ae596545c712
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Steroid lactones > Cardenolides and derivatives > Cardenolide glycosides and derivatives
IUPAC Name (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-[(2R,3R,4S,5S,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H46O10/c1-17-24(34)25(37-3)26(38-4)27(40-17)41-19-5-10-29(16-32)21-6-9-28(2)20(18-13-23(33)39-15-18)8-12-31(28,36)22(21)7-11-30(29,35)14-19/h13,16-17,19-22,24-27,34-36H,5-12,14-15H2,1-4H3/t17-,19+,20-,21+,22-,24+,25+,26-,27+,28-,29+,30+,31+/m1/s1
InChI Key BGGIZHKHJBQRTI-HJKWRMQUSA-N
Popularity 10 references in papers

Physical and Chemical Properties

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Molecular Formula C31H46O10
Molecular Weight 578.70 g/mol
Exact Mass 578.30909766 g/mol
Topological Polar Surface Area (TPSA) 141.00 Ų
XlogP 0.40

Synonyms

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59015-79-1
CHEMBL449686
NSC 382876
Card-20(22)-enolide, 3-((6-deoxy-2,3-di-O-methyl-beta-D-galactopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)-
(3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-[(2R,3R,4S,5S,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde

2D Structure

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2D Structure of Strebloside

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.18% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.89% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.02% 94.45%
CHEMBL1994 P08235 Mineralocorticoid receptor 95.82% 100.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.86% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.77% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.50% 97.09%
CHEMBL241 Q14432 Phosphodiesterase 3A 88.46% 92.94%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.44% 95.89%
CHEMBL253 P34972 Cannabinoid CB2 receptor 88.26% 97.25%
CHEMBL3714130 P46095 G-protein coupled receptor 6 87.67% 97.36%
CHEMBL4208 P20618 Proteasome component C5 87.29% 90.00%
CHEMBL2581 P07339 Cathepsin D 87.18% 98.95%
CHEMBL3492 P49721 Proteasome Macropain subunit 87.10% 90.24%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.35% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 85.30% 85.14%
CHEMBL1871 P10275 Androgen Receptor 83.83% 96.43%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 83.16% 91.71%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.85% 82.69%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.81% 97.14%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.24% 94.00%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 81.49% 94.78%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 80.93% 86.00%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 80.89% 96.77%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Streblus asper

Cross-Links

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PubChem 21123718
LOTUS LTS0220104
wikiData Q104935521