Stemocurtisinol N-Oxide

Details

Top
Internal ID 1deb42e2-e31d-4db5-906a-69cfa54262df
Taxonomy Organoheterocyclic compounds > Furofurans
IUPAC Name (5Z)-5-[(1R,6S,9S,10R,11R,12S)-6-[(1S)-1-hydroxypropyl]-12-methyl-5-oxido-14,15-dioxa-5-azoniatetracyclo[7.5.1.01,11.05,10]pentadecan-13-ylidene]-4-methoxy-3-methylfuran-2-one
SMILES (Canonical) CCC(C1CCC2C3[N+]1(CCCC4(C3C(C(=C5C(=C(C(=O)O5)C)OC)O4)C)O2)[O-])O
SMILES (Isomeric) CC[C@@H]([C@@H]1CC[C@H]2[C@@H]3[N+]1(CCC[C@@]4([C@@H]3[C@@H](/C(=C/5\C(=C(C(=O)O5)C)OC)/O4)C)O2)[O-])O
InChI InChI=1S/C22H31NO7/c1-5-14(24)13-7-8-15-17-16-11(2)19(20-18(27-4)12(3)21(25)28-20)30-22(16,29-15)9-6-10-23(13,17)26/h11,13-17,24H,5-10H2,1-4H3/b20-19-/t11-,13-,14-,15-,16+,17-,22+,23?/m0/s1
InChI Key GQHSQVDONZAQMO-UAMZZLTQSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C22H31NO7
Molecular Weight 421.50 g/mol
Exact Mass 421.21005233 g/mol
Topological Polar Surface Area (TPSA) 92.30 Ų
XlogP 2.30

Synonyms

Top
CHEMBL1642207

2D Structure

Top
2D Structure of Stemocurtisinol N-Oxide

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.31% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.85% 85.14%
CHEMBL2581 P07339 Cathepsin D 96.32% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.44% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.68% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.45% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.15% 99.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.83% 95.56%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.89% 97.14%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 86.80% 96.38%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.86% 92.62%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 85.15% 98.75%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.89% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.86% 95.89%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.75% 94.00%
CHEMBL3401 O75469 Pregnane X receptor 82.67% 94.73%
CHEMBL3359 P21462 Formyl peptide receptor 1 81.60% 93.56%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.40% 96.47%
CHEMBL301 P24941 Cyclin-dependent kinase 2 81.33% 91.23%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 80.25% 92.88%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Stemona curtisii

Cross-Links

Top
PubChem 53320016
LOTUS LTS0078057
wikiData Q105015391