Spumigin G

Details

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Internal ID 61473c78-fa79-421a-873b-1f508745e6d2
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > N-acyl-alpha amino acids and derivatives
IUPAC Name (2S,4S)-N-[5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(2R)-2-[[(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino]-4-phenylbutanoyl]-4-methylpyrrolidine-2-carboxamide
SMILES (Canonical) CC1CC(N(C1)C(=O)C(CCC2=CC=CC=C2)NC(=O)C(CC3=CC=C(C=C3)O)O)C(=O)NC(CCCN=C(N)N)C=O
SMILES (Isomeric) C[C@H]1C[C@H](N(C1)C(=O)[C@@H](CCC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=C(C=C3)O)O)C(=O)NC(CCCN=C(N)N)C=O
InChI InChI=1S/C31H42N6O6/c1-20-16-26(28(41)35-23(19-38)8-5-15-34-31(32)33)37(18-20)30(43)25(14-11-21-6-3-2-4-7-21)36-29(42)27(40)17-22-9-12-24(39)13-10-22/h2-4,6-7,9-10,12-13,19-20,23,25-27,39-40H,5,8,11,14-18H2,1H3,(H,35,41)(H,36,42)(H4,32,33,34)/t20-,23?,25+,26-,27+/m0/s1
InChI Key YGAGCUYKOBGAQX-SYCDWYGJSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C31H42N6O6
Molecular Weight 594.70 g/mol
Exact Mass 594.31658308 g/mol
Topological Polar Surface Area (TPSA) 200.00 Ų
XlogP 1.40

Synonyms

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(2S,4S)-N-[5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(2R)-2-[[(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino]-4-phenylbutanoyl]-4-methylpyrrolidine-2-carboxamide
(2S,4S)-N-(5-(diaminomethylideneamino)-1-oxopentan-2-yl)-1-((2R)-2-(((2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl)amino)-4-phenylbutanoyl)-4-methylpyrrolidine-2-carboxamide
(2S,4S)-N-(5-Carbamimidamido-1-oxopentan-2-yl)-1-((2R)-2-(((2R)-1,2-dihydroxy-3-(4-hydroxyphenyl)propylidene)amino)-4-phenylbutanoyl)-4-methylpyrrolidine-2-carboximidate
(2S,4S)-N-(5-Carbamimidamido-1-oxopentan-2-yl)-1-[(2R)-2-{[(2R)-1,2-dihydroxy-3-(4-hydroxyphenyl)propylidene]amino}-4-phenylbutanoyl]-4-methylpyrrolidine-2-carboximidate
SPU G
RefChem:185075
(2S,4S)-N-(5-guanidino-1-oxopentan-2-yl)-1-((R)-2-((R)-2-hydroxy-3-(4-hydroxyphenyl)propanamido)-4-phenylbutanoyl)-4-methylpyrrolidine-2-carboxamide
CHEBI:219896
DTXSID901333784
(4S)-N-{5-[(Diaminomethylidene)amino]-1-oxopentan-2-yl}-1-[(2R)-2-{[(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino}-4-phenylbutanoyl]-4-methyl-L-prolinamide

2D Structure

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2D Structure of Spumigin G

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.62% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.23% 96.09%
CHEMBL3837 P07711 Cathepsin L 96.74% 96.61%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.95% 95.56%
CHEMBL4072 P07858 Cathepsin B 95.45% 93.67%
CHEMBL3060 Q9Y345 Glycine transporter 2 95.02% 99.17%
CHEMBL2514 O95665 Neurotensin receptor 2 94.42% 100.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.25% 91.11%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 93.32% 100.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 92.36% 95.89%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 92.22% 97.64%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 91.62% 90.71%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 91.52% 82.69%
CHEMBL3891 P07384 Calpain 1 91.45% 93.04%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.03% 97.09%
CHEMBL221 P23219 Cyclooxygenase-1 89.61% 90.17%
CHEMBL233 P35372 Mu opioid receptor 89.52% 97.93%
CHEMBL1255126 O15151 Protein Mdm4 89.48% 90.20%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.72% 86.33%
CHEMBL6136 O60341 Lysine-specific histone demethylase 1 88.58% 95.58%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 87.92% 98.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.59% 93.56%
CHEMBL2535 P11166 Glucose transporter 87.57% 98.75%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 87.18% 96.67%
CHEMBL4227 P25090 Lipoxin A4 receptor 87.15% 100.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.78% 94.45%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 86.66% 97.21%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 86.66% 95.50%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 85.75% 100.00%
CHEMBL5028 O14672 ADAM10 85.50% 97.50%
CHEMBL340 P08684 Cytochrome P450 3A4 84.88% 91.19%
CHEMBL2431 P31751 Serine/threonine-protein kinase AKT2 84.88% 98.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.27% 95.89%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.77% 93.00%
CHEMBL236 P41143 Delta opioid receptor 81.91% 99.35%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.88% 97.14%
CHEMBL4208 P20618 Proteasome component C5 81.57% 90.00%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 80.51% 89.33%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139588808
LOTUS LTS0160181
wikiData Q104246318