Spongistatin 3

Details

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Internal ID cf0ccf09-e25f-42ee-8f1b-bd928c098315
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Glycosyl compounds > C-glycosyl compounds
IUPAC Name [(1R,3R,9R,10R,11R,14R,15S,17R,18S,19S,23Z,25S,27R,29R,31R,36S,37R,38S,41R,43R,49S)-11-[(4R,5E)-7-chloro-4-hydroxy-2-methylideneocta-5,7-dienyl]-3,10,14,15,17,27,43-heptahydroxy-31-methoxy-18,36,38,43,49-pentamethyl-39-methylidene-7,35-dioxo-8,12,45,46,47,48,50-heptaoxaheptacyclo[39.3.1.11,5.19,13.115,19.125,29.129,33]pentacont-23-en-37-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C61H93ClO20/c1-32(18-40(64)17-16-34(3)62)19-51-53(70)55-38(7)56(76-51)57(71)61(73)30-49(68)36(5)50(82-61)15-13-11-12-14-43-21-41(65)26-59(78-43)29-46(74-10)23-45(79-59)24-48(67)37(6)54(75-39(8)63)35(4)33(2)20-47-28-58(9,72)31-60(81-47)27-42(66)22-44(80-60)25-52(69)77-55/h12,14,16-17,35-38,40-47,49-51,53-57,64-66,68,70-73H,1-3,11,13,15,18-31H2,4-10H3/b14-12-,17-16+/t35-,36-,37+,38+,40-,41+,42+,43+,44?,45?,46+,47+,49+,50-,51+,53+,54+,55+,56?,57+,58+,59-,60-,61-/m0/s1
InChI Key VGULLEUAAMBZTQ-YGHPZBLNSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C61H93ClO20
Molecular Weight 1181.80 g/mol
Exact Mass 1180.5948730 g/mol
Topological Polar Surface Area (TPSA) 296.00 Ų
XlogP 4.40

Synonyms

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VGULLEUAAMBZTQ-YGHPZBLNSA-N

2D Structure

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2D Structure of Spongistatin 3

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.47% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 99.23% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.67% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.22% 97.25%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 95.37% 96.77%
CHEMBL2581 P07339 Cathepsin D 95.26% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.28% 95.56%
CHEMBL230 P35354 Cyclooxygenase-2 94.11% 89.63%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.11% 85.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.91% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.67% 86.33%
CHEMBL1902 P62942 FK506-binding protein 1A 91.32% 97.05%
CHEMBL4227 P25090 Lipoxin A4 receptor 91.08% 100.00%
CHEMBL3401 O75469 Pregnane X receptor 90.47% 94.73%
CHEMBL340 P08684 Cytochrome P450 3A4 90.17% 91.19%
CHEMBL5255 O00206 Toll-like receptor 4 89.62% 92.50%
CHEMBL5957 P21589 5'-nucleotidase 89.03% 97.78%
CHEMBL1994 P08235 Mineralocorticoid receptor 88.57% 100.00%
CHEMBL221 P23219 Cyclooxygenase-1 86.43% 90.17%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 86.31% 95.71%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.62% 95.89%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 84.71% 91.07%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 83.92% 95.00%
CHEMBL2413 P32246 C-C chemokine receptor type 1 83.81% 89.50%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 83.16% 95.50%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.72% 93.00%
CHEMBL6136 O60341 Lysine-specific histone demethylase 1 81.94% 95.58%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 81.61% 96.90%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.54% 97.09%
CHEMBL2996 Q05655 Protein kinase C delta 81.51% 97.79%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 81.22% 92.62%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.91% 97.14%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 80.83% 85.00%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 80.66% 95.50%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 80.57% 91.03%
CHEMBL299 P17252 Protein kinase C alpha 80.40% 98.03%
CHEMBL4208 P20618 Proteasome component C5 80.38% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 6479881
LOTUS LTS0076190
wikiData Q105286072