Splenocin I

Details

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Internal ID e600f0dd-1b66-4bab-9b59-50a3fa67ae1a
Taxonomy Benzenoids > Benzene and substituted derivatives > Benzoic acids and derivatives > Acylaminobenzoic acid and derivatives
IUPAC Name [(2R,3S,6S,7R,8R)-8-benzyl-3-[(3-formamido-2-hydroxybenzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] benzoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H30N2O9/c1-18-25(33-28(36)22-14-9-15-24(26(22)35)32-17-34)31(39)41-19(2)27(42-29(37)21-12-7-4-8-13-21)23(30(38)40-18)16-20-10-5-3-6-11-20/h3-15,17-19,23,25,27,35H,16H2,1-2H3,(H,32,34)(H,33,36)/t18-,19+,23-,25+,27+/m1/s1
InChI Key CDFGTWCLDDDNOL-YMWAZFFASA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C31H30N2O9
Molecular Weight 574.60 g/mol
Exact Mass 574.19513054 g/mol
Topological Polar Surface Area (TPSA) 157.00 Ų
XlogP 4.60

Synonyms

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((2R,3S,6S,7R,8R)-8-benzyl-3-((3-formamido-2-hydroxybenzoyl)amino)-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl) benzoate
[(2R,3S,6S,7R,8R)-8-benzyl-3-[(3-formamido-2-hydroxybenzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] benzoate
N-((2R,3S,6S,7R,8R)-7-(Benzoyloxy)-8-benzyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-3-yl)-2-hydroxy-3-((hydroxymethylidene)amino)benzene-1-carboximidate
N-[(2R,3S,6S,7R,8R)-7-(Benzoyloxy)-8-benzyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-3-yl]-2-hydroxy-3-[(hydroxymethylidene)amino]benzene-1-carboximidate
RefChem:184982
CHEMBL502486
CHEBI:215592
[(2R,3S,6S,7R,8R)-8-benzyl-3-[(3-ormamido-2-hydroxybenzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] benzoate

2D Structure

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2D Structure of Splenocin I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.25% 98.95%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 96.94% 89.34%
CHEMBL1951 P21397 Monoamine oxidase A 96.85% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.33% 95.56%
CHEMBL221 P23219 Cyclooxygenase-1 92.22% 90.17%
CHEMBL1293294 P51151 Ras-related protein Rab-9A 91.81% 87.67%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.79% 99.23%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.36% 96.09%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 89.62% 81.11%
CHEMBL3060 Q9Y345 Glycine transporter 2 89.48% 99.17%
CHEMBL3401 O75469 Pregnane X receptor 89.20% 94.73%
CHEMBL1293249 Q13887 Kruppel-like factor 5 85.96% 86.33%
CHEMBL2535 P11166 Glucose transporter 85.27% 98.75%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 84.98% 93.03%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.82% 91.11%
CHEMBL340 P08684 Cytochrome P450 3A4 82.94% 91.19%
CHEMBL3891 P07384 Calpain 1 82.82% 93.04%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 81.94% 95.50%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.89% 95.89%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 81.51% 93.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 42626144
LOTUS LTS0091502
wikiData Q104954343