Spiroaspertrione A

Details

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Internal ID d4d320b5-84c3-4339-834b-4ca14b495a19
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Cyclic ketones > Cyclohexenones
IUPAC Name (1S,4'aS,7S,8'aS,11R)-5',5',7,8'a,10-pentamethylspiro[3-oxatricyclo[5.3.2.01,5]dodeca-5,9-diene-11,2'-4,4a-dihydro-3H-naphthalene]-1',4,6',8-tetrone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H28O5/c1-14-10-18(27)22(4)11-15-19(28)30-13-25(14,15)24(12-22)9-6-16-21(2,3)17(26)7-8-23(16,5)20(24)29/h7-8,10-11,16H,6,9,12-13H2,1-5H3/t16-,22+,23-,24-,25-/m0/s1
InChI Key MIDLCYFJWSEKFO-NNKUPEEWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C25H28O5
Molecular Weight 408.50 g/mol
Exact Mass 408.19367399 g/mol
Topological Polar Surface Area (TPSA) 77.50 Ų
XlogP 2.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Spiroaspertrione A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.85% 95.56%
CHEMBL1937 Q92769 Histone deacetylase 2 93.46% 94.75%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.98% 82.69%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.84% 97.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.16% 91.11%
CHEMBL2581 P07339 Cathepsin D 91.61% 98.95%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 90.74% 94.80%
CHEMBL1994 P08235 Mineralocorticoid receptor 90.01% 100.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.84% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.55% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.53% 89.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 83.79% 93.99%
CHEMBL230 P35354 Cyclooxygenase-2 83.37% 89.63%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.58% 97.14%
CHEMBL2850 P49840 Glycogen synthase kinase-3 alpha 81.73% 88.84%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 81.63% 96.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.64% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139094862
LOTUS LTS0205201
wikiData Q105164512