Ser-phe

Details

• Internal ID: 2076dfa4-c34d-4d05-ad91-745241416bbf
• Taxonomy: Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Dipeptides
• IUPAC Name: (2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoic acid
• SMILES (Canonical): C1=CC=C(C=C1)CC(C(=O)O)NC(=O)C(CO)N
• SMILES (Isomeric): C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)[C@H](CO)N
• InChI: InChI=1S/C12H16N2O4/c13-9(7-15)11(16)14-10(12(17)18)6-8-4-2-1-3-5-8/h1-5,9-10,15H,6-7,13H2,(H,14,16)(H,17,18)/t9-,10-/m0/s1
• InChI Key: PPQRSMGDOHLTBE-UWVGGRQHSA-N
• Popularity: 18 references in papers

Physical and Chemical Properties

• Molecular Formula: C₁₂H₁₆N₂O₄
• Molecular Weight: 252.27 g/mol
• Exact Mass: 252.11100700 g/mol
• Topological Polar Surface Area (TPSA): 113.00 Ų
• XlogP: -3.50

Synonyms

• H-Ser-Phe-OH
• 16875-28-8
• Serinylphenylalanine
• L-seryl-L-phenylalanine
• CHEBI:71029
• CHEMBL3321990
• (S)-2-((S)-2-Amino-3-hydroxypropanamido)-3-phenylpropanoic acid
• SF dipeptide
• (2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoic acid
• (2S)-2-{[(2S)-2-amino-3-hydroxypropanoyl]amino}-3-phenylpropanoic acid
• S-F Dipeptide
• Seryl-phenylalanine
• l-serylphenylalanine
• L-Ser-L-Phe
• L-Serinyl-L-Phenylalanine
• Serine Phenylalanine dipeptide
• Serine-Phenylalanine dipeptide
• SCHEMBL9622556
• HY-P4509
• BDBM50049557
• MFCD00037254
• CS-0654527
• Q27139262
• (2S)-2-[(2S)-2-AMINO-3-HYDROXYPROPANAMIDO]-3-PHENYLPROPANOIC ACID

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL2581	P07339	Cathepsin D	97.86%	98.95%
CHEMBL221	P23219	Cyclooxygenase-1	97.83%	90.17%
CHEMBL1255126	O15151	Protein Mdm4	97.28%	90.20%
CHEMBL3060	Q9Y345	Glycine transporter 2	89.89%	99.17%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	89.18%	96.09%
CHEMBL3091268	Q92753	Nuclear receptor ROR-beta	89.03%	95.50%
CHEMBL3108638	O15164	Transcription intermediary factor 1-alpha	88.98%	95.56%
CHEMBL1907591	P30926	Neuronal acetylcholine receptor; alpha4/beta4	87.55%	100.00%
CHEMBL2035	P08912	Muscarinic acetylcholine receptor M5	86.58%	94.62%
CHEMBL216	P11229	Muscarinic acetylcholine receptor M1	86.13%	94.23%
CHEMBL3359	P21462	Formyl peptide receptor 1	86.02%	93.56%
CHEMBL1795139	Q8IU80	Transmembrane protease serine 6	85.79%	98.33%
CHEMBL4040	P28482	MAP kinase ERK2	85.59%	83.82%
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	83.37%	91.11%
CHEMBL2327	P21452	Neurokinin 2 receptor	82.34%	98.89%
CHEMBL3976	Q9UHL4	Dipeptidyl peptidase II	81.77%	92.29%
CHEMBL4793	Q86TI2	Dipeptidyl peptidase IX	81.16%	96.95%
CHEMBL4394	Q9NYA1	Sphingosine kinase 1	80.62%	96.03%

Plants that contains it

• Arabidopsis thaliana

Cross-Links

• PubChem: 7009598
• LOTUS: LTS0153266
• wikiData: Q27139262