Septicine

Details

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Internal ID 2b47605e-1202-46fe-b677-ba7666c696b4
Taxonomy Phenylpropanoids and polyketides > Stilbenes
IUPAC Name (8aR)-6,7-bis(3,4-dimethoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C24H29NO4/c1-26-21-9-7-16(12-23(21)28-3)19-14-18-6-5-11-25(18)15-20(19)17-8-10-22(27-2)24(13-17)29-4/h7-10,12-13,18H,5-6,11,14-15H2,1-4H3/t18-/m1/s1
InChI Key MXMHNOVMTJDCLE-GOSISDBHSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C24H29NO4
Molecular Weight 395.50 g/mol
Exact Mass 395.20965841 g/mol
Topological Polar Surface Area (TPSA) 40.20 Ų
XlogP 3.70

Synonyms

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(8aR)-6,7-bis(3,4-dimethoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine
DTXSID60444567
RefChem:182429
DTXCID60395388
24316-18-5
42922-10-1
(R)-Septicine
(R)-6,7-Bis(3,4-dimethoxyphenyl)-1,2,3,5,8,8a-hexahydroindolizine
CHEMBL1092163
SCHEMBL30435126

2D Structure

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2D Structure of Septicine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3438 Q05513 Protein kinase C zeta 96.72% 88.48%
CHEMBL5747 Q92793 CREB-binding protein 96.18% 95.12%
CHEMBL241 Q14432 Phosphodiesterase 3A 95.12% 92.94%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.81% 96.09%
CHEMBL5203 P33316 dUTP pyrophosphatase 94.43% 99.18%
CHEMBL5608 Q16288 NT-3 growth factor receptor 94.28% 95.89%
CHEMBL2581 P07339 Cathepsin D 94.09% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.11% 86.33%
CHEMBL264 Q9Y5N1 Histamine H3 receptor 89.07% 91.43%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 88.06% 95.78%
CHEMBL2243 O00519 Anandamide amidohydrolase 87.09% 97.53%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 86.74% 89.62%
CHEMBL4355 O14976 Serine/threonine-protein kinase GAK 86.48% 89.32%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 85.72% 90.95%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.58% 97.09%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.46% 97.14%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.12% 94.00%
CHEMBL3023 Q9NRA0 Sphingosine kinase 2 83.65% 95.61%
CHEMBL4247 Q9UM73 ALK tyrosine kinase receptor 82.71% 96.86%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.66% 95.56%
CHEMBL1907599 P05556 Integrin alpha-4/beta-1 82.32% 92.86%
CHEMBL1938212 Q9UPP1 Histone lysine demethylase PHF8 81.03% 98.33%
CHEMBL1907601 P11802 Cyclin-dependent kinase 4/cyclin D1 80.94% 98.99%
CHEMBL3192 Q9BY41 Histone deacetylase 8 80.71% 93.99%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Ficus septica

Cross-Links

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PubChem 10763252
NPASS NPC11147
ChEMBL CHEMBL1092163
LOTUS LTS0174410
wikiData Q82262739