Sclerotiotide B

Details

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Internal ID b2a512fc-17b1-4d67-875a-a8b33f963aa4
Taxonomy Phenylpropanoids and polyketides > Macrolactams
IUPAC Name (2E,4E)-N-[(3S,6S,9S)-3,4,7-trimethyl-2,5,8-trioxo-6-propan-2-yl-1,4,7-triazacyclododec-9-yl]hexa-2,4-dienamide
SMILES (Canonical) CC=CC=CC(=O)NC1CCCNC(=O)C(N(C(=O)C(N(C1=O)C)C(C)C)C)C
SMILES (Isomeric) C/C=C/C=C/C(=O)N[C@H]1CCCNC(=O)[C@@H](N(C(=O)[C@@H](N(C1=O)C)C(C)C)C)C
InChI InChI=1S/C21H34N4O4/c1-7-8-9-12-17(26)23-16-11-10-13-22-19(27)15(4)24(5)21(29)18(14(2)3)25(6)20(16)28/h7-9,12,14-16,18H,10-11,13H2,1-6H3,(H,22,27)(H,23,26)/b8-7+,12-9+/t15-,16-,18-/m0/s1
InChI Key YDMIIJJQQVACFZ-DHHXFONYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C21H34N4O4
Molecular Weight 406.50 g/mol
Exact Mass 406.25800558 g/mol
Topological Polar Surface Area (TPSA) 98.80 Ų
XlogP 1.70

Synonyms

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CHEMBL1164384

2D Structure

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2D Structure of Sclerotiotide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.26% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.56% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.62% 97.25%
CHEMBL4072 P07858 Cathepsin B 92.72% 93.67%
CHEMBL1907598 P05106 Integrin alpha-V/beta-3 92.45% 95.71%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 91.35% 91.03%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 89.08% 93.03%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 88.64% 90.71%
CHEMBL5103 Q969S8 Histone deacetylase 10 88.13% 90.08%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.99% 89.00%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 85.80% 95.71%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.60% 99.23%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.53% 97.09%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 84.96% 90.24%
CHEMBL4208 P20618 Proteasome component C5 84.80% 90.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.37% 93.00%
CHEMBL3524 P56524 Histone deacetylase 4 83.88% 92.97%
CHEMBL1937 Q92769 Histone deacetylase 2 83.84% 94.75%
CHEMBL4588 P22894 Matrix metalloproteinase 8 83.84% 94.66%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 83.72% 96.47%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.41% 91.11%
CHEMBL321 P14780 Matrix metalloproteinase 9 83.17% 92.12%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.83% 94.45%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 81.92% 89.34%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.27% 93.56%
CHEMBL1075317 P61964 WD repeat-containing protein 5 80.13% 96.33%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 46849844
LOTUS LTS0130112
wikiData Q77378996