Scillirosidin

Details

Top
Internal ID a9087c1f-98f5-41ed-8d2d-0f238b68dd0d
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Steroid lactones > Bufanolides and derivatives
IUPAC Name [(3S,6R,8S,9R,10R,13R,14R,17R)-3,8,14-trihydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-2,3,6,7,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H34O7/c1-15(27)33-20-13-25(30)21(23(2)9-6-17(28)12-19(20)23)8-10-24(3)18(7-11-26(24,25)31)16-4-5-22(29)32-14-16/h4-5,12,14,17-18,20-21,28,30-31H,6-11,13H2,1-3H3/t17-,18+,20+,21+,23-,24+,25-,26+/m0/s1
InChI Key SOJXCEWHLPYBAF-KDVWZPTCSA-N
Popularity 3 references in papers

Physical and Chemical Properties

Top
Molecular Formula C26H34O7
Molecular Weight 458.50 g/mol
Exact Mass 458.23045342 g/mol
Topological Polar Surface Area (TPSA) 113.00 Ų
XlogP 1.20

Synonyms

Top
507-59-5
6beta-acetoxy-3beta,8alpha,14-trihydroxybufa-4,20,22-trienolide
[(3S,6R,8S,9R,10R,13R,14R,17R)-3,8,14-trihydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-2,3,6,7,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-yl] acetate
NSC 7534
BRN 0065119
CHEBI:37417
Q27117135
BUFA-4,20,22-TRIENOLIDE, 3-beta,6-beta,8,14-TETRAHYDROXY-, 6-ACETATE
Bufa-4,20,22-trienolide, 6-(acetyloxy)-3,8,14-trihydroxy-, (3-beta,6-beta)-

2D Structure

Top
2D Structure of Scillirosidin

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.24% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.94% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.14% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.16% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.80% 97.09%
CHEMBL2581 P07339 Cathepsin D 91.31% 98.95%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.25% 95.89%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.93% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 88.51% 97.25%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.59% 94.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.99% 92.62%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.40% 99.23%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.17% 100.00%
CHEMBL4208 P20618 Proteasome component C5 83.18% 90.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.22% 86.33%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 81.83% 96.77%
CHEMBL3922 P50579 Methionine aminopeptidase 2 81.33% 97.28%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Drimia maritima
Drimia sanguinea

Cross-Links

Top
PubChem 12315397
LOTUS LTS0208832
wikiData Q27117135