Saroclide B

Details

Top
Internal ID 76f76ff1-65cf-445b-92c5-b382e1acf313
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3R,8E,11R,14R)-3-benzyl-8-methyl-11-propyl-12-oxa-1,4-diazabicyclo[12.3.0]heptadec-8-ene-2,5,7,13-tetrone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H32N2O5/c1-3-8-19-13-12-17(2)22(28)16-23(29)26-20(15-18-9-5-4-6-10-18)24(30)27-14-7-11-21(27)25(31)32-19/h4-6,9-10,12,19-21H,3,7-8,11,13-16H2,1-2H3,(H,26,29)/b17-12+/t19-,20-,21-/m1/s1
InChI Key YSNFMBLAIYADSY-UQUBZZJZSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C25H32N2O5
Molecular Weight 440.50 g/mol
Exact Mass 440.23112213 g/mol
Topological Polar Surface Area (TPSA) 92.80 Ų
XlogP 3.70

Synonyms

Top
CHEMBL4277899

2D Structure

Top
2D Structure of Saroclide B

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.62% 98.95%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 95.25% 97.64%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 94.69% 82.38%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.28% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.73% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.16% 96.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.23% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.69% 97.09%
CHEMBL3524 P56524 Histone deacetylase 4 89.10% 92.97%
CHEMBL5103 Q969S8 Histone deacetylase 10 88.85% 90.08%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 88.07% 93.03%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.66% 99.23%
CHEMBL5805 Q9NR97 Toll-like receptor 8 85.43% 96.25%
CHEMBL1902 P62942 FK506-binding protein 1A 85.21% 97.05%
CHEMBL253 P34972 Cannabinoid CB2 receptor 84.25% 97.25%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.76% 97.14%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.88% 93.00%
CHEMBL3401 O75469 Pregnane X receptor 82.73% 94.73%
CHEMBL4447 Q9Y337 Kallikrein 5 81.94% 87.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.57% 86.33%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 80.94% 92.67%
CHEMBL4523377 Q86WV6 Stimulator of interferon genes protein 80.37% 95.48%
CHEMBL6007 O75762 Transient receptor potential cation channel subfamily A member 1 80.32% 92.17%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 139589957
LOTUS LTS0182414
wikiData Q105360098