Sanguirubine

Details

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Internal ID ea0fb8bd-7711-4015-806d-5137363684da
Taxonomy Alkaloids and derivatives > Benzophenanthridine alkaloids > Quaternary benzophenanthridine alkaloids
IUPAC Name 3,16,17-trimethoxy-12-methyl-6,8-dioxa-12-azoniapentacyclo[11.8.0.02,10.05,9.014,19]henicosa-1(13),2,4,9,11,14,16,18,20-nonaene
SMILES (Canonical) C[N+]1=CC2=C3C(=CC(=C2C4=C1C5=CC(=C(C=C5C=C4)OC)OC)OC)OCO3
SMILES (Isomeric) C[N+]1=CC2=C3C(=CC(=C2C4=C1C5=CC(=C(C=C5C=C4)OC)OC)OC)OCO3
InChI InChI=1S/C22H20NO5/c1-23-10-15-20(18(26-4)9-19-22(15)28-11-27-19)13-6-5-12-7-16(24-2)17(25-3)8-14(12)21(13)23/h5-10H,11H2,1-4H3/q+1
InChI Key FUAPOWMHFINSMM-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C22H20NO5+
Molecular Weight 378.40 g/mol
Exact Mass 378.13414774 g/mol
Topological Polar Surface Area (TPSA) 50.00 Ų
XlogP 4.50

Synonyms

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C12230
AC1L78VM
AC1Q701F
CHEBI:32118
benzo[c]-1,3-dioxolo[4,5-i]phenanthridinium, 5,9,10-trimethoxy-12-methyl-
Q27114791
3,16,17-trimethoxy-12-methyl-6,8-dioxa-12-azoniapentacyclo[11.8.0.02,10.05,9.014,19]henicosa-1(13),2,4,9,11,14,16,18,20-nonaene

2D Structure

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2D Structure of Sanguirubine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 97.04% 96.77%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.12% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.85% 91.11%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 91.47% 89.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.78% 95.56%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 90.65% 94.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.66% 92.62%
CHEMBL241 Q14432 Phosphodiesterase 3A 89.45% 92.94%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 89.35% 85.30%
CHEMBL3192 Q9BY41 Histone deacetylase 8 88.48% 93.99%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.01% 86.33%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 87.77% 96.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.52% 96.09%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 86.78% 94.80%
CHEMBL5925 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 85.49% 92.38%
CHEMBL2535 P11166 Glucose transporter 83.41% 98.75%
CHEMBL2581 P07339 Cathepsin D 82.68% 98.95%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 81.51% 82.67%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 81.47% 91.79%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Sanguinaria canadensis

Cross-Links

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PubChem 356662
LOTUS LTS0077263
wikiData Q27114791