Rostratin D

Details

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Internal ID f3f52a4d-c348-4708-98ca-aa76b5d44d6a
Taxonomy Organoheterocyclic compounds > Diazinanes > Piperazines > Thiodioxopiperazines > Epipolythiodioxopiperazines
IUPAC Name (1R,4R,5R,6R,9S,11R,14R,15R,16R,19S)-5,15-dihydroxy-6,16-bis(sulfanyl)-21,22-dithia-3,13-diazahexacyclo[9.9.2.01,13.03,11.04,9.014,19]docosane-2,8,12,18-tetrone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C18H20N2O6S4/c21-7-1-9(27)13(23)11-5(7)3-17-15(25)20-12-6(8(22)2-10(28)14(12)24)4-18(20,30-29-17)16(26)19(11)17/h5-6,9-14,23-24,27-28H,1-4H2/t5-,6-,9-,10-,11-,12-,13+,14+,17-,18-/m1/s1
InChI Key GCSPJPVOPHGWRM-XPMVLQEKSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C18H20N2O6S4
Molecular Weight 488.60 g/mol
Exact Mass 488.02042106 g/mol
Topological Polar Surface Area (TPSA) 168.00 Ų
XlogP -1.70

Synonyms

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CHEBI:66313
(3R,4R,4aR,6aR,7aS,10R,11R,11aR,13aR,14aR)-4,11-dihydroxy-3,10-disulfanyldecahydro-1H,7H-6a,13a-epidithiopyrazino[1,2-a:4,5-a']diindole-1,6,8,13(7aH)-tetrone
(1R,4R,5R,6R,9S,11R,14R,15R,16R,19S)-5,15-dihydroxy-6,16-bis(sulfanyl)-21,22-dithia-3,13-diazahexacyclo(9.9.2.01,13.03,11.04,9.014,19)docosane-2,8,12,18-tetrone
(1R,4R,5R,6R,9S,11R,14R,15R,16R,19S)-5,15-dihydroxy-6,16-bis(sulfanyl)-21,22-dithia-3,13-diazahexacyclo[9.9.2.01,13.03,11.04,9.014,19]docosane-2,8,12,18-tetrone
(3R,4R,4aR,6aR,7aS,10R,11R,11aR,13aR,14aR)-4,11-dihydroxy-3,10-disulfanyldecahydro-1H,7H-6a,13a-epidithiopyrazino(1,2-a:4,5-a')diindole-1,6,8,13(7aH)-tetrone
RefChem:179940
752236-19-4
CHEMBL515973
Q27134857

2D Structure

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2D Structure of Rostratin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.11% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.03% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.47% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 87.01% 83.82%
CHEMBL2581 P07339 Cathepsin D 85.22% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 84.86% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.24% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 82.06% 85.14%
CHEMBL3137261 O14744 PRMT5/MEP50 complex 81.81% 100.00%
CHEMBL325 Q13547 Histone deacetylase 1 81.02% 95.92%
CHEMBL1929 P47989 Xanthine dehydrogenase 81.01% 96.12%
CHEMBL4208 P20618 Proteasome component C5 80.39% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11488689
LOTUS LTS0116217
wikiData Q27134857