Romucosine D

Details

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Internal ID 4542f3f3-7c17-4ac4-a785-6a9634342ac8
Taxonomy Alkaloids and derivatives > Aporphines
IUPAC Name methyl 1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-carboxylate
SMILES (Canonical) COC1=CC2=C(CC3C4=C2C(=C(C=C4CCN3C(=O)OC)OC)OC)C=C1
SMILES (Isomeric) COC1=CC2=C(CC3C4=C2C(=C(C=C4CCN3C(=O)OC)OC)OC)C=C1
InChI InChI=1S/C21H23NO5/c1-24-14-6-5-12-9-16-18-13(7-8-22(16)21(23)27-4)10-17(25-2)20(26-3)19(18)15(12)11-14/h5-6,10-11,16H,7-9H2,1-4H3
InChI Key GIUSYZFFMYWEAY-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C21H23NO5
Molecular Weight 369.40 g/mol
Exact Mass 369.15762283 g/mol
Topological Polar Surface Area (TPSA) 57.20 Ų
XlogP 3.30

Synonyms

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(+)-Romucosine D

2D Structure

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2D Structure of Romucosine D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.35% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.11% 91.11%
CHEMBL4208 P20618 Proteasome component C5 94.69% 90.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.35% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.50% 99.17%
CHEMBL2535 P11166 Glucose transporter 91.24% 98.75%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 89.40% 91.79%
CHEMBL2056 P21728 Dopamine D1 receptor 89.03% 91.00%
CHEMBL2581 P07339 Cathepsin D 88.93% 98.95%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 88.05% 95.89%
CHEMBL261 P00915 Carbonic anhydrase I 87.63% 96.76%
CHEMBL340 P08684 Cytochrome P450 3A4 86.58% 91.19%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 86.21% 91.03%
CHEMBL217 P14416 Dopamine D2 receptor 86.17% 95.62%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 85.80% 93.40%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.74% 95.89%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.99% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.96% 86.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.35% 97.09%
CHEMBL3437 Q16853 Amine oxidase, copper containing 81.92% 94.00%
CHEMBL3438 Q05513 Protein kinase C zeta 81.29% 88.48%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 81.20% 92.62%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.07% 90.71%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Annona mucosa

Cross-Links

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PubChem 85102142
LOTUS LTS0128225
wikiData Q105009228