Rhizoxin D

Details

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Internal ID f90a867d-5c55-4a24-b40c-42a8dfa1278b
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Terpene lactones
IUPAC Name (1R,3E,7S,9S,10E,12E,14R,15R)-9-hydroxy-7-[(2S,3R,4E,6E,8E)-3-methoxy-4,8-dimethyl-9-(2-methyl-1,3-oxazol-4-yl)nona-4,6,8-trien-2-yl]-10,14-dimethyl-6,16-dioxabicyclo[13.3.1]nonadeca-3,10,12-triene-5,17-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C35H47NO7/c1-22(17-29-21-41-27(6)36-29)11-8-14-25(4)35(40-7)26(5)32-20-30(37)23(2)12-9-13-24(3)31-18-28(19-34(39)42-31)15-10-16-33(38)43-32/h8-14,16-17,21,24,26,28,30-32,35,37H,15,18-20H2,1-7H3/b11-8+,13-9+,16-10+,22-17+,23-12+,25-14+/t24-,26+,28-,30+,31-,32+,35+/m1/s1
InChI Key BDCIVUTULLELHY-BRPJXHCYSA-N
Popularity 13 references in papers

Physical and Chemical Properties

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Molecular Formula C35H47NO7
Molecular Weight 593.70 g/mol
Exact Mass 593.33525284 g/mol
Topological Polar Surface Area (TPSA) 108.00 Ų
XlogP 6.90

Synonyms

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(1R,3E,7S,9S,10E,12E,14R,15R)-9-hydroxy-7-[(2S,3R,4E,6E,8E)-3-methoxy-4,8-dimethyl-9-(2-methyl-1,3-oxazol-4-yl)nona-4,6,8-trien-2-yl]-10,14-dimethyl-6,16-dioxabicyclo[13.3.1]nonadeca-3,10,12-triene-5,17-dione
InChI=1/C35H47NO7/c1-22(17-29-21-41-27(6)36-29)11-8-14-25(4)35(40-7)26(5)32-20-30(37)23(2)12-9-13-24(3)31-18-28(19-34(39)42-31)15-10-16-33(38)43-32/h8-14,16-17,21,24,26,28,30-32,35,37H,15,18-20H2,1-7H3/b11-8+,13-9+,16-10+,22-17+,23-12+,25-14+/t24-,26+,28-

2D Structure

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2D Structure of Rhizoxin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.63% 99.23%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.52% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.78% 86.33%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 89.02% 93.40%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 88.87% 93.65%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.10% 91.11%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 86.50% 100.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.18% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 85.30% 96.09%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 85.28% 97.33%
CHEMBL3401 O75469 Pregnane X receptor 85.15% 94.73%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.57% 90.71%
CHEMBL230 P35354 Cyclooxygenase-2 84.48% 89.63%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 84.27% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 83.99% 99.17%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.90% 94.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.45% 93.56%
CHEMBL1937 Q92769 Histone deacetylase 2 82.37% 94.75%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 82.32% 94.80%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 82.31% 96.77%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.59% 93.03%
CHEMBL4073 P09237 Matrix metalloproteinase 7 81.00% 97.56%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 80.69% 97.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 9808665
LOTUS LTS0135991
wikiData Q104923844