Rhinoclactone D

Details

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Internal ID b7eff944-9a32-42d2-9c5e-8bdda5b2d8ca
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (4S,10S)-15-chloro-16-hydroxy-10,18-dimethoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-2,7,12-trione
SMILES (Canonical) CC1CCC(=O)CCC(CC(=O)CC2=C(C(=CC(=C2C(=O)O1)OC)O)Cl)OC
SMILES (Isomeric) C[C@H]1CCC(=O)CC[C@@H](CC(=O)CC2=C(C(=CC(=C2C(=O)O1)OC)O)Cl)OC
InChI InChI=1S/C20H25ClO7/c1-11-4-5-12(22)6-7-14(26-2)8-13(23)9-15-18(20(25)28-11)17(27-3)10-16(24)19(15)21/h10-11,14,24H,4-9H2,1-3H3/t11-,14-/m0/s1
InChI Key DEMKQUIZOFIHRZ-FZMZJTMJSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C20H25ClO7
Molecular Weight 412.90 g/mol
Exact Mass 412.1288808 g/mol
Topological Polar Surface Area (TPSA) 99.10 Ų
XlogP 2.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Rhinoclactone D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.40% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.27% 95.56%
CHEMBL1951 P21397 Monoamine oxidase A 92.78% 91.49%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.85% 94.45%
CHEMBL2581 P07339 Cathepsin D 91.81% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.04% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.97% 86.33%
CHEMBL241 Q14432 Phosphodiesterase 3A 88.85% 92.94%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 88.74% 94.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.34% 95.89%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 87.31% 93.40%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.04% 97.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.09% 97.09%
CHEMBL2535 P11166 Glucose transporter 84.94% 98.75%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.65% 89.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.61% 92.62%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 83.18% 96.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 82.97% 99.17%
CHEMBL5203 P33316 dUTP pyrophosphatase 81.20% 99.18%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.65% 91.07%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 80.53% 82.67%
CHEMBL217 P14416 Dopamine D2 receptor 80.10% 95.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 125416179
LOTUS LTS0025573
wikiData Q104977331