Rhinoclactone B

Details

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Internal ID 13c21d05-3736-44c1-9ca0-a953d8dc9ab7
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (4S,7R)-15-chloro-7,16-dihydroxy-18-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-2,12-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C19H25ClO6/c1-11-7-8-12(21)5-3-4-6-13(22)9-14-17(19(24)26-11)16(25-2)10-15(23)18(14)20/h10-12,21,23H,3-9H2,1-2H3/t11-,12+/m0/s1
InChI Key NCXOJEYZRDHVQA-NWDGAFQWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C19H25ClO6
Molecular Weight 384.80 g/mol
Exact Mass 384.1339662 g/mol
Topological Polar Surface Area (TPSA) 93.10 Ų
XlogP 3.00

Synonyms

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(4S,7R)-15-chloro-7,16-dihydroxy-18-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-2,12-dione
(4S,7R)-15-chloro-7,16-dihydroxy-18-methoxy-4-methyl-3-oxabicyclo(12.4.0)octadeca-1(18),14,16-triene-2,12-dione
RefChem:179166
CHEBI:206487

2D Structure

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2D Structure of Rhinoclactone B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.45% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.05% 95.56%
CHEMBL2581 P07339 Cathepsin D 94.79% 98.95%
CHEMBL2535 P11166 Glucose transporter 91.20% 98.75%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.00% 86.33%
CHEMBL241 Q14432 Phosphodiesterase 3A 89.79% 92.94%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 89.74% 96.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.50% 92.62%
CHEMBL1951 P21397 Monoamine oxidase A 88.57% 91.49%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.01% 95.89%
CHEMBL3192 Q9BY41 Histone deacetylase 8 87.99% 93.99%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.89% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.09% 96.09%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 86.73% 94.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.67% 97.14%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.27% 96.77%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.13% 89.00%
CHEMBL5203 P33316 dUTP pyrophosphatase 83.71% 99.18%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 83.17% 82.67%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.16% 97.09%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.87% 90.71%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.61% 93.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682690
LOTUS LTS0081598
wikiData Q105177435