Rel-(8S)-19,20-dihydro-9,20-dihydroxy-8-methoxy-9,18-diepifumitremorgin C

Details

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Internal ID 9cacccd8-8f6b-4344-8536-596e28d2f9f7
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyridoindoles > Beta carbolines
IUPAC Name (1R,2R,12S,15R)-1-hydroxy-12-(2-hydroxy-2-methylpropyl)-2,7-dimethoxy-10,13,19-triazapentacyclo[11.7.0.03,11.04,9.015,19]icosa-3(11),4(9),5,7-tetraene-14,20-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C23H29N3O6/c1-22(2,29)11-16-18-17(13-8-7-12(31-3)10-14(13)24-18)19(32-4)23(30)21(28)25-9-5-6-15(25)20(27)26(16)23/h7-8,10,15-16,19,24,29-30H,5-6,9,11H2,1-4H3/t15-,16+,19-,23-/m1/s1
InChI Key IQQGHQDLZFLSGU-QIEVIBBNSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C23H29N3O6
Molecular Weight 443.50 g/mol
Exact Mass 443.20563565 g/mol
Topological Polar Surface Area (TPSA) 115.00 Ų
XlogP 0.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Rel-(8S)-19,20-dihydro-9,20-dihydroxy-8-methoxy-9,18-diepifumitremorgin C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.90% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.55% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.32% 97.25%
CHEMBL1902 P62942 FK506-binding protein 1A 97.12% 97.05%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.60% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 95.66% 95.89%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.35% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.17% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.60% 95.56%
CHEMBL241 Q14432 Phosphodiesterase 3A 92.40% 92.94%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 90.29% 86.92%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 90.24% 91.03%
CHEMBL3192 Q9BY41 Histone deacetylase 8 89.86% 93.99%
CHEMBL1871 P10275 Androgen Receptor 89.54% 96.43%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.42% 94.00%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 88.52% 90.24%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 88.33% 93.40%
CHEMBL4208 P20618 Proteasome component C5 87.73% 90.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 86.22% 92.62%
CHEMBL1907 P15144 Aminopeptidase N 86.20% 93.31%
CHEMBL1293249 Q13887 Kruppel-like factor 5 85.62% 86.33%
CHEMBL1951 P21397 Monoamine oxidase A 85.33% 91.49%
CHEMBL2535 P11166 Glucose transporter 85.15% 98.75%
CHEMBL5203 P33316 dUTP pyrophosphatase 81.94% 99.18%
CHEMBL3524 P56524 Histone deacetylase 4 81.08% 92.97%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.09% 93.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139583828
LOTUS LTS0121445
wikiData Q75067966