Pyristriatin B

Details

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Internal ID f1de1c34-9e8d-4e3c-bb5e-84e6128222ab
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Sesquiterpenoids
IUPAC Name 2-hydroxy-1-[(1R,2R,5R,10R,11S,18S)-11-hydroxy-18-methoxy-2,5-dimethyl-8-propan-2-yl-19-oxa-15-azapentacyclo[11.6.1.02,10.05,9.017,20]icosa-8,13,15,17(20)-tetraen-16-yl]ethanone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H35NO5/c1-13(2)15-6-7-25(3)8-9-26(4)21(20(15)25)16(29)10-14-11-27-22(17(30)12-28)19-18(14)23(26)32-24(19)31-5/h11,13,16,21,23-24,28-29H,6-10,12H2,1-5H3/t16-,21+,23-,24-,25+,26+/m0/s1
InChI Key GOSSDHHYVCWSCT-IHMRMOLWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C26H35NO5
Molecular Weight 441.60 g/mol
Exact Mass 441.25152322 g/mol
Topological Polar Surface Area (TPSA) 88.90 Ų
XlogP 2.50

Synonyms

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CHEMBL4082991

2D Structure

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2D Structure of Pyristriatin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.41% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.48% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.93% 94.45%
CHEMBL221 P23219 Cyclooxygenase-1 95.39% 90.17%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.52% 97.25%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.49% 86.33%
CHEMBL2581 P07339 Cathepsin D 90.68% 98.95%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 89.92% 95.89%
CHEMBL1937 Q92769 Histone deacetylase 2 88.35% 94.75%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.43% 94.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.98% 93.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.82% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.74% 90.71%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 85.72% 91.07%
CHEMBL1907598 P05106 Integrin alpha-V/beta-3 84.36% 95.71%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.02% 99.17%
CHEMBL2243 O00519 Anandamide amidohydrolase 83.80% 97.53%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 83.31% 91.24%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.18% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.45% 97.09%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 82.31% 94.33%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 81.41% 96.38%
CHEMBL5028 O14672 ADAM10 81.29% 97.50%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.79% 96.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.45% 100.00%
CHEMBL4208 P20618 Proteasome component C5 80.05% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 137646727
LOTUS LTS0132629
wikiData Q105107117