4-(2-(4-fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl)pyridine

Details

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Internal ID 6defbbf5-9248-4d22-bc13-68a409a160ba
Taxonomy Organoheterocyclic compounds > Pyrroles > Substituted pyrroles > Phenylpyrroles
IUPAC Name 4-[2-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrrol-3-yl]pyridine
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H22FN3/c1-25-12-8-16(9-13-25)20-14-19(15-6-10-23-11-7-15)21(24-20)17-2-4-18(22)5-3-17/h2-7,10-11,14,16,24H,8-9,12-13H2,1H3
InChI Key RBWNFHXBUDPAIO-UHFFFAOYSA-N
Popularity 20 references in papers

Physical and Chemical Properties

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Molecular Formula C21H22FN3
Molecular Weight 335.40 g/mol
Exact Mass 335.17977588 g/mol
Topological Polar Surface Area (TPSA) 31.90 Ų
XlogP 3.60

Synonyms

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MBP146-78
Pyridine, 4-[2-(4-fluorophenyl)-5-(1-methyl-4-piperidinyl)-1H-pyrrol-3-yl]-
4-[2-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrrol-3-yl]pyridine
CHEMBL190228
MMV688703
4-(2-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrrol-3-yl)pyridine
4-[2-(4-Fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl]pyridine
SCHEMBL3290870
DTXSID30333333
BCP29592
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 4-(2-(4-fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl)pyridine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.93% 96.09%
CHEMBL240 Q12809 HERG 98.43% 89.76%
CHEMBL2581 P07339 Cathepsin D 98.25% 98.95%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 95.85% 93.40%
CHEMBL4145 Q9UKV0 Histone deacetylase 9 95.43% 85.49%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 95.24% 93.03%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 94.83% 100.00%
CHEMBL255 P29275 Adenosine A2b receptor 94.80% 98.59%
CHEMBL262 P49841 Glycogen synthase kinase-3 beta 93.52% 95.72%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 92.94% 91.79%
CHEMBL226 P30542 Adenosine A1 receptor 91.06% 95.93%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 90.54% 92.68%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 90.32% 91.03%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 89.78% 82.69%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 89.70% 99.09%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 88.35% 96.38%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.02% 95.89%
CHEMBL3524 P56524 Histone deacetylase 4 87.96% 92.97%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 87.91% 95.78%
CHEMBL2828 P48730 Casein kinase I delta 87.90% 93.08%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 87.88% 80.96%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 87.84% 85.11%
CHEMBL4158 P49327 Fatty acid synthase 87.59% 82.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.92% 86.33%
CHEMBL1937 Q92769 Histone deacetylase 2 86.43% 94.75%
CHEMBL2000 P03952 Plasma kallikrein 86.41% 93.92%
CHEMBL1994 P08235 Mineralocorticoid receptor 86.28% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.98% 90.71%
CHEMBL4940 P07195 L-lactate dehydrogenase B chain 85.85% 95.53%
CHEMBL3116 P50750 Cyclin-dependent kinase 9 85.76% 96.31%
CHEMBL1938212 Q9UPP1 Histone lysine demethylase PHF8 85.73% 98.33%
CHEMBL221 P23219 Cyclooxygenase-1 85.51% 90.17%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 85.36% 90.71%
CHEMBL3192 Q9BY41 Histone deacetylase 8 85.11% 93.99%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 84.99% 96.00%
CHEMBL5747 Q92793 CREB-binding protein 84.74% 95.12%
CHEMBL2243 O00519 Anandamide amidohydrolase 84.26% 97.53%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 84.16% 93.65%
CHEMBL5203 P33316 dUTP pyrophosphatase 84.04% 99.18%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 83.96% 93.10%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.92% 94.00%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 83.88% 91.71%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 83.17% 96.69%
CHEMBL1868 P17948 Vascular endothelial growth factor receptor 1 83.16% 96.47%
CHEMBL2163176 P41229 Lysine-specific demethylase 5C 83.07% 93.00%
CHEMBL2424504 P29375 Lysine-specific demethylase 5A 82.92% 99.23%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 82.37% 90.24%
CHEMBL344 Q99705 Melanin-concentrating hormone receptor 1 81.75% 92.50%
CHEMBL5903 Q04771 Activin receptor type-1 81.68% 89.93%
CHEMBL4937 P49674 Casein kinase I epsilon 81.35% 92.71%
CHEMBL2535 P11166 Glucose transporter 81.02% 98.75%
CHEMBL217 P14416 Dopamine D2 receptor 81.01% 95.62%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 80.55% 90.95%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 80.40% 96.21%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 80.00% 85.14%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 500899
LOTUS LTS0208868
wikiData Q82098545