Pseudodestruxin A

Details

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Internal ID 25329a73-9c32-464e-ba31-62ac0693396d
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (3S,10S,13S,16S,19S)-16-benzyl-13-[(2S)-butan-2-yl]-11,14-dimethyl-3,10-bis(2-methylpropyl)-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C37H57N5O7/c1-9-25(6)32-37(48)40(7)29(20-23(2)3)33(44)38-18-17-31(43)49-30(21-24(4)5)36(47)42-19-13-16-28(42)34(45)39-27(35(46)41(32)8)22-26-14-11-10-12-15-26/h10-12,14-15,23-25,27-30,32H,9,13,16-22H2,1-8H3,(H,38,44)(H,39,45)/t25-,27-,28-,29-,30-,32-/m0/s1
InChI Key MDOMEJMFUHIERW-KZECFEFESA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C37H57N5O7
Molecular Weight 683.90 g/mol
Exact Mass 683.42579917 g/mol
Topological Polar Surface Area (TPSA) 145.00 Ų
XlogP 4.80

Synonyms

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CHEMBL505239
SCHEMBL3132509

2D Structure

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2D Structure of Pseudodestruxin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.84% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.24% 96.09%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 95.05% 97.64%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.75% 95.56%
CHEMBL3524 P56524 Histone deacetylase 4 93.68% 92.97%
CHEMBL333 P08253 Matrix metalloproteinase-2 93.16% 96.31%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 92.91% 82.38%
CHEMBL255 P29275 Adenosine A2b receptor 90.22% 98.59%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 90.06% 93.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 90.01% 97.25%
CHEMBL5103 Q969S8 Histone deacetylase 10 89.81% 90.08%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.88% 95.89%
CHEMBL226 P30542 Adenosine A1 receptor 88.79% 95.93%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.24% 86.33%
CHEMBL1902 P62942 FK506-binding protein 1A 87.85% 97.05%
CHEMBL3202 P48147 Prolyl endopeptidase 87.81% 90.65%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.30% 85.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.02% 94.45%
CHEMBL4616 Q92847 Ghrelin receptor 86.72% 92.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.52% 97.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 84.29% 93.03%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 84.16% 95.34%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.35% 97.14%
CHEMBL5203 P33316 dUTP pyrophosphatase 83.32% 99.18%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.04% 99.23%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 82.77% 90.93%
CHEMBL228 P31645 Serotonin transporter 82.64% 95.51%
CHEMBL4588 P22894 Matrix metalloproteinase 8 82.42% 94.66%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 80.90% 92.67%
CHEMBL3401 O75469 Pregnane X receptor 80.32% 94.73%
CHEMBL217 P14416 Dopamine D2 receptor 80.31% 95.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10078314
LOTUS LTS0210820
wikiData Q75064079