pseudoaeruginosin NS1

Details

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Internal ID 0b2333e5-0119-4c1d-b357-a34a392ec172
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > N-acyl-alpha amino acids and derivatives
IUPAC Name (2S,4S)-N-[5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl]-4-methylpyrrolidine-2-carboxamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H42N6O5/c1-3-4-5-8-24(36)32-22(15-19-9-11-21(35)12-10-19)26(38)33-16-18(2)14-23(33)25(37)31-20(17-34)7-6-13-30-27(28)29/h9-12,17-18,20,22-23,35H,3-8,13-16H2,1-2H3,(H,31,37)(H,32,36)(H4,28,29,30)/t18-,20?,22-,23-/m0/s1
InChI Key ULFMNSXBTYDMFI-JLWWHIBLSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C27H42N6O5
Molecular Weight 530.70 g/mol
Exact Mass 530.32166846 g/mol
Topological Polar Surface Area (TPSA) 180.00 Ų
XlogP 1.70

Synonyms

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DTXSID301334746
(2S,4S)-N-(5-(diaminomethylideneamino)-1-oxopentan-2-yl)-1-((2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl)-4-methylpyrrolidine-2-carboxamide
(2S,4S)-N-[5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl]-4-methylpyrrolidine-2-carboxamide
RefChem:176890
DTXCID801764219
(2S,4S)-N-((2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl)-1-((2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl)-4-methylpyrrolidine-2-carboxamide
(2S,4S)-N-(5-guanidino-1-oxopentan-2-yl)-1-(hexanoyl-L-tyrosyl)-4-methylpyrrolidine-2-carboxamide
CHEBI:212838
N-Hexanoyl-L-tyrosyl-(4S)-N-{5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-4-methyl-L-prolinamide

2D Structure

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2D Structure of pseudoaeruginosin NS1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.65% 98.95%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.98% 99.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.53% 96.09%
CHEMBL3837 P07711 Cathepsin L 98.11% 96.61%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 96.60% 90.71%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.04% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.04% 94.45%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 94.57% 91.81%
CHEMBL4072 P07858 Cathepsin B 93.98% 93.67%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 93.29% 93.10%
CHEMBL2514 O95665 Neurotensin receptor 2 93.20% 100.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.91% 82.69%
CHEMBL3891 P07384 Calpain 1 92.86% 93.04%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 92.41% 92.08%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.14% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.07% 97.09%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 90.99% 97.23%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 90.12% 95.89%
CHEMBL2535 P11166 Glucose transporter 89.71% 98.75%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 89.62% 97.21%
CHEMBL340 P08684 Cytochrome P450 3A4 89.18% 91.19%
CHEMBL2431 P31751 Serine/threonine-protein kinase AKT2 89.17% 98.33%
CHEMBL3492 P49721 Proteasome Macropain subunit 88.91% 90.24%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 87.93% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 87.57% 100.00%
CHEMBL230 P35354 Cyclooxygenase-2 86.64% 89.63%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.39% 86.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.30% 93.56%
CHEMBL1255126 O15151 Protein Mdm4 85.88% 90.20%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 85.67% 98.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.21% 95.89%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 85.15% 96.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 85.09% 100.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.35% 93.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 83.86% 97.64%
CHEMBL4208 P20618 Proteasome component C5 83.17% 90.00%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 82.64% 92.86%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 82.43% 95.00%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 82.24% 97.29%
CHEMBL259 P32245 Melanocortin receptor 4 81.93% 95.38%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 81.34% 96.95%
CHEMBL4644 P41968 Melanocortin receptor 3 80.81% 99.52%
CHEMBL4608 P33032 Melanocortin receptor 5 80.08% 97.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 146683670
LOTUS LTS0082725
wikiData Q105275076