Prochaetoglobosin II

Details

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Internal ID 4330c098-3f09-43df-9fa1-ba944a9887a0
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indoles > 3-alkylindoles
IUPAC Name (1S,3Z,7E,9S,11E,13S,16S,17R,18S)-18-(1H-indol-3-ylmethyl)-7,9,15,16-tetramethyl-19-azatricyclo[11.7.0.01,17]icosa-3,7,11,14-tetraene-2,5,20-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H36N2O3/c1-19-8-7-9-24-16-21(3)22(4)30-28(17-23-18-33-27-11-6-5-10-26(23)27)34-31(37)32(24,30)29(36)13-12-25(35)15-20(2)14-19/h5-7,9-14,16,18-19,22,24,28,30,33H,8,15,17H2,1-4H3,(H,34,37)/b9-7+,13-12-,20-14+/t19-,22+,24-,28-,30-,32+/m0/s1
InChI Key ZWMGAOFPDWVLLV-WVXRVHBYSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C32H36N2O3
Molecular Weight 496.60 g/mol
Exact Mass 496.27259301 g/mol
Topological Polar Surface Area (TPSA) 79.00 Ų
XlogP 4.80

Synonyms

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CHEBI:68740
(3S,3aR,4S,6aS,7E,10S,11E,15Z,17aS)-3-(1H-indol-3-ylmethyl)-4,5,10,12-tetramethyl-2,3,3a,4,6a,9,10,13-octahydro-1H-cyclotrideca[d]isoindole-1,14,17-trione
(1S,3Z,7E,9S,11E,13S,16S,17R,18S)-18-(1H-indol-3-ylmethyl)-7,9,15,16-tetramethyl-19-azatricyclo(11.7.0.01,17)icosa-3,7,11,14-tetraene-2,5,20-trione
(1S,3Z,7E,9S,11E,13S,16S,17R,18S)-18-(1H-indol-3-ylmethyl)-7,9,15,16-tetramethyl-19-azatricyclo[11.7.0.01,17]icosa-3,7,11,14-tetraene-2,5,20-trione
(3S,3aR,4S,6aS,7E,10S,11E,15Z,17aS)-3-(1H-indol-3-ylmethyl)-4,5,10,12-tetramethyl-2,3,3a,4,6a,9,10,13-octahydro-1H-cyclotrideca(d)isoindole-1,14,17-trione
RefChem:176121
Q27137159

2D Structure

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2D Structure of Prochaetoglobosin II

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.31% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.68% 95.56%
CHEMBL2581 P07339 Cathepsin D 96.54% 98.95%
CHEMBL3310 Q96DB2 Histone deacetylase 11 96.16% 88.56%
CHEMBL2996 Q05655 Protein kinase C delta 93.08% 97.79%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.12% 85.14%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.88% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.54% 96.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 91.06% 93.99%
CHEMBL1937 Q92769 Histone deacetylase 2 89.66% 94.75%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.51% 94.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.06% 99.23%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 88.90% 97.64%
CHEMBL255 P29275 Adenosine A2b receptor 88.85% 98.59%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.61% 97.09%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 88.33% 89.62%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.67% 89.00%
CHEMBL3045 P05771 Protein kinase C beta 85.75% 97.63%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.70% 92.62%
CHEMBL2535 P11166 Glucose transporter 85.32% 98.75%
CHEMBL5103 Q969S8 Histone deacetylase 10 84.80% 90.08%
CHEMBL5805 Q9NR97 Toll-like receptor 8 81.19% 96.25%
CHEMBL4302 P08183 P-glycoprotein 1 81.10% 92.98%
CHEMBL213 P08588 Beta-1 adrenergic receptor 80.98% 95.56%
CHEMBL4208 P20618 Proteasome component C5 80.06% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 71768072
LOTUS LTS0096300
wikiData Q27137159