Porwenin A

Details

Top
Internal ID 4beafa78-ff04-4c41-9633-272fee01bd6d
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Colensane and clerodane diterpenoids
IUPAC Name (4aS,7R,8S,8aR)-8-[(Z)-5-hydroxy-3-(hydroxymethyl)pent-3-enyl]-7,8-dimethyl-4-methylidene-2,3,5,6,7,8a-hexahydro-1H-naphthalene-4a-carboxylic acid
SMILES (Canonical) CC1CCC2(C(C1(C)CCC(=CCO)CO)CCCC2=C)C(=O)O
SMILES (Isomeric) C[C@@H]1CC[C@@]2([C@@H]([C@@]1(C)CC/C(=C/CO)/CO)CCCC2=C)C(=O)O
InChI InChI=1S/C20H32O4/c1-14-7-11-20(18(23)24)15(2)5-4-6-17(20)19(14,3)10-8-16(13-22)9-12-21/h9,14,17,21-22H,2,4-8,10-13H2,1,3H3,(H,23,24)/b16-9-/t14-,17-,19+,20-/m1/s1
InChI Key HVZFLMOCARQHTL-PBUBQFPOSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C20H32O4
Molecular Weight 336.50 g/mol
Exact Mass 336.23005950 g/mol
Topological Polar Surface Area (TPSA) 77.80 Ų
XlogP 3.50

Synonyms

Top
(4aS,7R,8S,8aR)-8-[(Z)-5-hydroxy-3-(hydroxymethyl)pent-3-enyl]-7,8-dimethyl-4-methylidene-2,3,5,6,7,8a-hexahydro-1H-naphthalene-4a-carboxylic acid

2D Structure

Top
2D Structure of Porwenin A

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.95% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.01% 91.11%
CHEMBL233 P35372 Mu opioid receptor 88.68% 97.93%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 88.49% 96.09%
CHEMBL2581 P07339 Cathepsin D 87.22% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.57% 95.56%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.98% 100.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.92% 93.00%
CHEMBL340 P08684 Cytochrome P450 3A4 83.84% 91.19%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 82.91% 95.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 81.53% 94.45%
CHEMBL5028 O14672 ADAM10 80.25% 97.50%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 11056820
LOTUS LTS0112475
wikiData Q105034560