Pleiomutinine

Details

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Internal ID 991bb82f-f80f-474d-8430-a8e53538c530
Taxonomy Alkaloids and derivatives > Pleiocarpaman alkaloids
IUPAC Name methyl (1R,4S,7S,14R,20R,21S,24E,25S,26S,38S,39R)-24-ethylidene-39-methyl-3,11,22,27-tetrazadodecacyclo[20.11.2.13,15.14,7.17,11.121,25.01,20.04,14.020,27.028,33.014,38.019,37]nonatriaconta-15(37),16,18,28,30,32-hexaene-26-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H46N4O2/c1-4-25-22-42-19-16-37-23-43-33-28(38-17-20-41-18-8-13-36(35(38)41)14-15-39(38,43)24(36)2)10-7-11-29(33)40(37)31(42)21-26(25)32(34(45)46-3)44(40)30-12-6-5-9-27(30)37/h4-7,9-12,24,26,31-32,35H,8,13-23H2,1-3H3/b25-4-/t24-,26+,31+,32+,35+,36+,37+,38-,39+,40-/m1/s1
InChI Key NHYWHOQGRJLYBG-XYIXMZRPSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C40H46N4O2
Molecular Weight 614.80 g/mol
Exact Mass 614.36207672 g/mol
Topological Polar Surface Area (TPSA) 39.30 Ų
XlogP 5.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Pleiomutinine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.55% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.70% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.57% 95.56%
CHEMBL2581 P07339 Cathepsin D 91.86% 98.95%
CHEMBL1914 P06276 Butyrylcholinesterase 91.57% 95.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.58% 86.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 90.26% 93.03%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.25% 91.11%
CHEMBL340 P08684 Cytochrome P450 3A4 88.37% 91.19%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.70% 99.23%
CHEMBL2535 P11166 Glucose transporter 87.20% 98.75%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.97% 82.69%
CHEMBL5028 O14672 ADAM10 85.53% 97.50%
CHEMBL2782 P35610 Acyl coenzyme A:cholesterol acyltransferase 1 81.93% 91.65%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 81.80% 94.08%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.34% 97.09%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.02% 90.71%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Hunteria zeylanica

Cross-Links

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PubChem 137628469
LOTUS LTS0113668
wikiData Q105179675