Planktopeptin BL843

Details

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Internal ID 94c61e85-4a61-490a-8deb-aafddce2544b
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name N-[(2R,5S,8S,11R,12S,15S,18S,21R)-8-[(2S)-butan-2-yl]-21-hydroxy-2-[(1S)-1-hydroxyethyl]-5-[(4-methoxyphenyl)methyl]-4,11-dimethyl-15-(2-methylpropyl)-3,6,9,13,16,22-hexaoxo-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]-5-oxopyrrolidine-2-carboxamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C41H61N7O12/c1-9-21(4)32-41(58)60-23(6)33(46-35(52)26-14-16-30(50)42-26)38(55)44-28(18-20(2)3)36(53)43-27-15-17-31(51)48(39(27)56)34(22(5)49)40(57)47(7)29(37(54)45-32)19-24-10-12-25(59-8)13-11-24/h10-13,20-23,26-29,31-34,49,51H,9,14-19H2,1-8H3,(H,42,50)(H,43,53)(H,44,55)(H,45,54)(H,46,52)/t21-,22-,23+,26?,27-,28-,29-,31+,32-,33-,34+/m0/s1
InChI Key NEBZXFVQFIUEIH-ZXVTVJSFSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C41H61N7O12
Molecular Weight 844.00 g/mol
Exact Mass 843.43782041 g/mol
Topological Polar Surface Area (TPSA) 262.00 Ų
XlogP 2.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Planktopeptin BL843

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.69% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.30% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 98.49% 83.82%
CHEMBL4072 P07858 Cathepsin B 96.02% 93.67%
CHEMBL4208 P20618 Proteasome component C5 95.87% 90.00%
CHEMBL333 P08253 Matrix metalloproteinase-2 95.46% 96.31%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.09% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.83% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 93.66% 99.17%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 93.24% 97.14%
CHEMBL255 P29275 Adenosine A2b receptor 93.13% 98.59%
CHEMBL226 P30542 Adenosine A1 receptor 92.39% 95.93%
CHEMBL4588 P22894 Matrix metalloproteinase 8 92.29% 94.66%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.75% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.48% 97.09%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 91.42% 95.71%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.14% 91.11%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.70% 95.89%
CHEMBL3192 Q9BY41 Histone deacetylase 8 90.46% 93.99%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.36% 85.14%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 88.55% 92.62%
CHEMBL5103 Q969S8 Histone deacetylase 10 88.47% 90.08%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.88% 86.33%
CHEMBL4616 Q92847 Ghrelin receptor 87.62% 92.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.28% 94.00%
CHEMBL1937 Q92769 Histone deacetylase 2 85.95% 94.75%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 85.82% 96.38%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 85.25% 97.64%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.92% 93.00%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 84.58% 89.67%
CHEMBL253 P34972 Cannabinoid CB2 receptor 84.44% 97.25%
CHEMBL321 P14780 Matrix metalloproteinase 9 84.35% 92.12%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 83.72% 94.33%
CHEMBL1949 P62937 Cyclophilin A 82.70% 98.57%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 82.67% 97.47%
CHEMBL283 P08254 Matrix metalloproteinase 3 82.48% 97.29%
CHEMBL3837 P07711 Cathepsin L 82.05% 96.61%
CHEMBL340 P08684 Cytochrome P450 3A4 81.30% 91.19%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.01% 89.00%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.80% 96.00%
CHEMBL3437 Q16853 Amine oxidase, copper containing 80.52% 94.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139583453
LOTUS LTS0071582
wikiData Q75062751